Liquid Chromatography

Fundamentals and Instrumentation

Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola

• Verlag: Elsevier
• Jahr: 2017
• ISBN:
  9780128093450
• Auflage: 2
• Thema: Biowissenschaften
• Thema: Wissenschaftliche Forschung & Methodik

Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field.

In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more.

This second edition addresses these new developments with updated chapters from the most expert researchers in the field.

• Emphasizes the integration of chromatographic methods and sample preparation
• Explains how liquid chromatography is used in different industrial sectors
• Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical)
• Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Inhaltsverzeichnis

• Cover image
• Title page
• Table of Contents
• Copyright
• Contributors
• Chapter 1: Milestones in the development of liquid chromatography
• Chapter 2: Kinetic theories of liquid chromatography
• Chapter 3: Column technology in liquid chromatography
• Chapter 4: Reversed-phase liquid chromatography
• Chapter 5: Secondary chemical equilibria in reversed-phase liquid chromatography
• Chapter 6: Hydrophilic interaction liquid chromatography
• Chapter 7: Hydrophobic interaction chromatography
• Chapter 8: Liquid-solid chromatography
• Chapter 9: Ion chromatography
• Chapter 10: Size-exclusion chromatography
• Chapter 11: Interaction polymer chromatography
• Chapter 12: Affinity chromatography
• Chapter 13: Solvent selection in liquid chromatography
• Chapter 14: Method development in liquid chromatography
• Chapter 15: Theory and practice of gradient elution liquid chromatography
• Chapter 16: Comprehensive two-dimensional liquid chromatography
• Chapter 17: General instrumentation in HPLC
• Chapter 18: Advanced spectroscopic detectors for identification and quantification: Mass spectrometry
• Chapter 19: Advanced IR and Raman detectors for identification and quantification
• Chapter 20: Advanced spectroscopic detectors for identification and quantification: Nuclear magnetic resonance
• Chapter 21: Data analysis
• Chapter 22: Validation of liquid chromatographic methods
• Chapter 23: Quantitative structure property (retention) relationships in liquid chromatography
• Chapter 24: Modeling of preparative liquid chromatography
• Chapter 25: Process concepts in preparative chromatography
• Chapter 26: Miniaturization and microfluidics
• Chapter 27: Nano-liquid chromatography
• Chapter 28: Capillary electrochromatography
• Chapter 29: Ultra-high performance liquid chromatography
• Index