Synthetic Peptide Vaccine Models

Design, Synthesis, Purification and Characterization

Mesut Karahan

• Editorial: CRC Press
• Año: 2021
• ISBN:
  9781000342772
• Edición: 1
• Categoría: Biowissenschaften
• Categoría: Mikrobiologie

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Índice

• Cover
• Half-Title
• Title
• Copyright
• Contents
• Acknowledgements
• Preface
• Editor Bio
• Contributors
• List of Figures
• List of Tables
• Chapter 1 Background
• Chapter 2 Introduction to Vaccination
• Chapter 3 Fundamentals of Modern Peptide Synthesis
• Chapter 4 Peptide Synthesis and Characterization Stages
• Chapter 5 Conjugation of Polymers with Biomolecules and Polymeric Vaccine Development Technologies
• Chapter 6 What Are Polymeric Carriers?
• Chapter 7 Conjugation and Other Methods in Polymeric Vaccines
• Chapter 8 Polymeric Nanoparticle Preparation Methods
• Chapter 9 Peptides in Brain Disorders
• Chapter 10 Pseudo-Proteins and Related Synthetic Amino Acid-Based Polymers Promising for Constructing Artificial Vaccines
• Chapter 11 Peptide Vaccines in Cancers
• Chapter 12 Antioxidant Effects of Peptides
• Chapter 13 Peptide Vaccine
• Chapter 14 Vaccine Adjuvants in Immunotoxicology
• Chapter 15 Role of Epigenetics in Immunity and Immune Response to Vaccination
• Chapter 16 “Omics” Technologies in Vaccine Research
• Chapter 17 Computer-Aided Epitope Identification and Design of Epitope Mimetics
• Index