Genetically Engineered Toxins

Arthur Frankel

• Éditeur: CRC Press
• Année: 2020
• ISBN:
  9781000147797
• Édition: 1
• Sujet: Technology & Engineering
• Sous-sujet: Applied Sciences

Presenting all preclinical and clinical information available on genetically engineered toxins, this unique, single-source reference provides the most up-to-date methods and practical examples for conducting clinical studies in toxin molecular biology.;Reviewing difficult problems and their solutions, Genetically Engineered Toxins discusses techniques for clo;ning, expressing, and purifying recombinant toxins and genetically modified recombinant toxins; documents structure-function relationships in toxins, including comparative information; supplies theory and illustrations of chimeric toxins; delineates the preclinical assessments of new reagents; and summarizes approaches to drug design.;With over 1100 literature citations, Genetically Engineered Toxins is an invaluable resource for biochemists, molecular biologists, biotechnologists, pharmacologists, toxicologists, X-ray crystallographers, enzymologists, oncologists, hematologists, immunologists, rheumatologists, botanists, and graduate-level students in molecular biology, biotechnology, and clinical oncology courses.

Table des matières

• Cover
• Half Title
• Title Page
• Copyright Page
• Dedication Page
• Introduction to the Series
• Preface
• Contents
• Contributors
• I Strategies and Techniques
• II Ricin
• III Plant Hemitoxins
• IV Fungal Ribotoxins
• V Diphtheria Toxin
• VI Pseudomonas Exotoxins
• VII Conclusions
• Appendix: Primary Amino Acid Sequences of Toxins
• Index