eBook - ePub

Genome Organization And Function In The Cell Nucleus

Name: Genome Organization And Function In The Cell Nucleus
Author: Karsten Rippe

Karsten Rippe,

English
ePUB (mobile friendly)
Available on iOS & Android

eBook - ePub

Genome Organization And Function In The Cell Nucleus

Karsten Rippe,

Book details

Table of contents

Citations

About This Book

By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained
knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair,
recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and
non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.

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Information

Publisher

Wiley-VCH

Year

2012

ISBN

9783527640003

Edition

Topic

Biological Sciences

Subtopic

Genetics & Genomics

Index

Biological Sciences

Cover
Contents
Title
Copyright
Dedication
Preface
List of Contributors
Chapter 1: Deciphering DNA Sequence Information
Chapter 2: DNA Methylation
Chapter 3: Nucleosomes as Control Elements for Accessing the Genome
Chapter 4: Histone Modifications and Their Role as Epigenetic Marks
Chapter 5: Chromatin Remodeling and Nucleosome Positioning
Chapter 6: The Folding of the Nucleosome Chain
Chapter 7: The Crowded Environment of the Genome
Chapter 8: The Nuclear Lamina as a Chromatin Organizer
Chapter 9: Three-Dimensional Architecture of Genomes
Chapter 10: Transcriptional Initiation: Frequency, Bursting, and Transcription Factories
Chapter 11: Processing of mRNA and Quality Control
Chapter 12: The Nucleolus
Chapter 13: Non-Coding RNAs as Regulators of Transcription and Genome Organization
Chapter 14: RNA Networks as Digital Control Circuits of Nuclear Functions
Chapter 15: DNA Replication and Inheritance of Epigenetic States
Chapter 16: Interplay and Quality Control of DNA Damage Repair Mechanisms
Chapter 17: Higher Order Chromatin Organization and Dynamics
Chapter 18: The Mitotic Chromosome: Structure and Mechanics
Chapter 19: Meiotic Chromosome Dynamics
Chapter 20: Understanding Genome Function: Quantitative Modeling of Chromatin Folding and Chromatin-Associated Processes
Index