Modern Tools for the Synthesis of Complex Bioactive Molecules
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Modern Tools for the Synthesis of Complex Bioactive Molecules
About This Book
All the latest tools needed to plan and perform the synthesis of complex bioactive molecules
Focusing on organic, organometallic, and bio-oriented processes, this book explores the impact and use of the latest synthetic tools for the synthesis of complex biologically active compounds. Readers will discover step by step how these synthetic tools have provided new, elegant solutions to many synthetic puzzles. Moreover, they will discover innovative methods that make it possible to control the exact connectivity of atoms within a molecule in order to set precise three-dimensional arrangements.
Modern Tools for the Synthesis of Complex Bioactive Molecules features sixteen chapters, each one written by one or more leading experts in organic synthesis from around the world. It covers a broad range of topics that enable readers to take advantage of the latest methods for synthesizing complex molecules, including:
- Modern catalysis, emphasizing key transformations such as C-H functionalizations, cross-couplings, gold-catalyzed reactions, metathesis-based syntheses, and asymmetric organocatalysis
- Eco-compatible transformations, including rearrangements and domino reactions
- Tools for the synthesis of carbohydrates and alkaloids
- New techniques, including the use of fluorous tags and engineered biosynthesis
The last two chapters explore target- and diversity-oriented organic synthesis as well as the use of DNA-based asymmetric catalysis, which are all promising tools for the successful synthesis of complex bioactive molecules.
Modern Tools for the Synthesis of Complex Bioactive Molecules is ideal for students and researchers who need to plan and perform the synthesis of complex molecules as efficiently as possible. The book's expert advice will help these readers quickly resolve a broad range of problems that can arise in organic syntheses.
Frequently asked questions
Information
Table of contents
- Cover
- Title Page
- Copyright
- Foreword
- Preface
- Contributors
- Chapter 1: CâH Functionalization: A New Strategy for the Synthesis of Biologically Active Natural Products
- Chapter 2: The Negishi Cross-Coupling in the Synthesis of Natural Products and Bioactive Molecules
- Chapter 3: Metal-Catalyzed CâHeteroatom Cross-Coupling Reactions
- Chapter 4: Golden Opportunities in the Synthesis of Natural Products and Biologically Active Compounds
- Chapter 5: Metathesis-Based Synthesis of Complex Bioactives
- Chapter 6: Enantioselective Organocatalysis: A Powerful Tool for the Synthesis of Bioactive Molecules
- Chapter 7: Asymmetric Phase-Transfer Catalysis
- Chapter 8: Rearrangements in Natural Product Synthesis
- Chapter 9: Domino Reactions in the Enantioselective Synthesis of Bioactive Natural Products
- Chapter 10: Fluorous Linker-Facilitated Synthesis of Biologically Interesting Molecules
- Chapter 11: The Evolution of Immobilized Reagents and Their Application in Flow Chemistry for the Synthesis of Natural Products and Pharmaceutical Compounds
- Chapter 12: Synthetic Approaches to Bioactive Carbohydrates
- Chapter 13: Ammonium Ylides as Building Blocks for Alkaloid Synthesis
- Chapter 14: Precursor-Directed Biosynthesis of Polyketide and Nonribosomal Peptide Natural Products
- Chapter 15: Target-Oriented and Diversity-Oriented Organic Synthesis
- Chapter 16: DNA as a Tool for Molecular Discovery
- Index