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- 691 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Handbook of Ion Channels
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About This Book
The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce
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Yes, you can access Handbook of Ion Channels by Jie Zheng, Matthew C. Trudeau, Jie Zheng, Matthew C. Trudeau in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.
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Table of contents
- Cover
- Contents
- Foreword: Early days of ion channels
- Preface
- Editors
- Contributors
- Part I: Basic Concepts
- Chapter 1: Electricity, Nerves, Batteries: A Short History
- Chapter 2: Ion Selectivity and Conductance
- Chapter 3: Basic Mechanisms of Voltage Sensing
- Chapter 4: Ligand-Dependent Gating Mechanism
- Chapter 5: Mechanosensitive Channels and their Emerging Gating Mechanisms
- Part II: Ion Channel Methods
- Chapter 6: Patch Clamping and Single-Channel Analysis
- Chapter 7: Models of Ion Channel Gating
- Chapter 8: Utilizing Markov Chains to Model Ion Channel Sequence Variation and Kinetics
- Chapter 9: Investigation of Ion Channel Structure Using Fluorescence Spectroscopy
- Chapter 10: A Practical Guide to Solving the Structure of an Ion Channel Protein
- Chapter 11: Structural Study of Ion Channels by Cryo-Electron Microscopy
- Chapter 12: Rosetta Structural Modeling
- Chapter 13: Genetic Methods for Studying Ion Channel Function in Physiology and Disease
- Chapter 14: Ion Channel Inhibitors
- Chapter 15: High-Throughput Methods for Ion Channels
- Part III: Ion Channel Families
- Chapter 16: Voltage-Gated Sodium Channels
- Chapter 17: BK Channels
- Chapter 18: Inward Rectifying Potassium Channels
- Chapter 19: Two-Pore Domain Potassium Channels
- Chapter 20: KCNQ Channels
- Chapter 21: Ionotropic Glutamate Receptors
- Chapter 22: 5-HT3 Receptors
- Chapter 23: GABAA Receptors
- Chapter 24: Cyclic NucleotideâGated Channels
- Chapter 25: Acid Sensing Ion Channels
- Chapter 26: Degenerin/ENaC Channels
- Chapter 27: TRPC Channels
- Chapter 28: TRPV Channels
- Chapter 29: TRPM Channels
- Chapter 30: TRPML Channels
- Chapter 31: CLC Chloride Channels and Transporters
- Chapter 32: Ca-Activated Chloride Channels
- Chapter 33: Store-Operated CRAC Channels
- Part IV: Ion Channel Regulation
- Chapter 34: Mechanism of G-Protein Regulation of K+ Channels
- Chapter 35: Calmodulin Regulation of Voltage-Gated Calcium Channels and Beyond
- Chapter 36: Phosphorylation of Voltage-Gated Ion Channels
- Chapter 37: Alternative Splicing
- Chapter 38: Single Transmembrane Regulatory Subunits of Voltage-Gated Potassium Channels
- Part V: Ion Channel Physiology and Diseases
- Chapter 39: Ion Channels of the Heart
- Chapter 40: Ion Channels in Pain
- Chapter 41: CLC-Related Proteins in Diseases
- Chapter 42: Cystic Fibrosis and the CFTR Anion Channel
- Chapter 43: Drugs Targeting Ion Channels
- Back Cover