Retinoids in Dermatology
- 234 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Retinoids in Dermatology
About This Book
Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures.
CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids
Published in association with the Journal of Dermatological Treatment.
Frequently asked questions
Information
Table 1.1 Vitamin A and Retinoids in Dermatology |
ā¢1900ā1910s/Stepp, Hopkins, McCollum, Osborne, Mendel/Fat-soluble growth factor extracted from eggs, milk, butter, liver ā¢1911/Funk/Vitamine ā¢1915/McCollum/Fat-soluble A ā¢1930/Moore/Carotene and vitamin A ā¢1931/Karrer/Chemical structure of vitamin A (retinol) ā¢1946/Arens/Vitamin A acid (tretinoin) ā¢1947/Isler/Synthesis of vitamin A (retinol) ā¢1960s/StĆ¼ttgen, Kligman/Topical effects of tretinoin ā¢1971/Bollag/Synthesis of isotretinoin ā¢1972/Synthesis of etretinate ā¢1973ā1976/First clinical studies with 13-cis retinoic acid ā¢1980/Palmskog/Synthesis of acitretin ā¢1997/Miller/Bexarotene in CTCL ā¢1999/Bollag/Alitretinoin in chronic hand dermatitis |
Table of contents
- Cover
- Half Title
- Series Page
- Title Page
- Copyright Page
- Contents
- Contributors
- 1. The Background of Retinoids
- 2. Mechanism of Action of Vitamin A
- 3. Mechanism of Action of Topical Retinoids
- 4. Mechanism of Action of Isotretinoin
- 5. Mechanism of Action of Acitretin
- 6. Mechanism of Action of Bexarotene
- 7. Mechanism of Action of Alitretinoin
- 8. Effects of Retinoids at the Cellular Level (Differentiation, Apoptosis, Autophagy, Cell Cycle Regulation, and Senescence)
- 9. Effects of Retinoids at the Systemic Level
- 10. New Aspects of Isotretinoin Teratogenicity
- 11. Mucocutaneous Side Effects
- 12. Ophthalmologic Side Effects
- 13. Musculoskeletal Side Effects
- 14. Neurologic Side Effects
- 15. Psychiatric Side Effects
- 16. Gastrointestinal Side Effects
- 17. Endocrine and Metabolic Side Effects
- 18. Other Systemic Side Effects: Cardiovascular, Pulmonary, Otolaryngorhinologic, Genitourinary, Renal, and Immunologic
- 19. Retinoids in Acne
- 20. Retinoids in Hidradenitis Suppurativa/Acne Inversa
- 21. Retinoids in Rosacea
- 22. Retinoids in Hair Disorders
- 23. Retinoids in Psoriasis
- 24. Retinoids in Keratinization Disorders
- 25. Retinoids in Antiaging Therapy
- 26. Retinoids in Other Skin Diseases
- 27. Retinoids in Lymphoma
- 28. Retinoids in Cutaneous Chemoprophylaxis
- 29. Guide to Good Clinical Practice for Vulnerable Populations (Infancy, Childhood, Fertile Period, Elderly)
- 30. Retinoids and Concomitant Surgery
- 31. Retinoids and Concomitant Aesthetic Procedures
- 32. Laboratory and Clinical Follow-Up
- 33. Teratogenicity and Registry Programs
- 34. Management of Vitamin A and Retinoid Side Effects
- 35. Future and Novel Unexplored Indications of Retinoids
- Index