Molecular, Cellular, and Tissue Engineering
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Molecular, Cellular, and Tissue Engineering

  1. 1,891 pages
  2. English
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eBook - PDF

Molecular, Cellular, and Tissue Engineering

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About This Book

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.

Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine.

More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.

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Information

Publisher
CRC Press
Year
2018
ISBN
9781439825310
Edition
1
Topic
Medicine
Subtopic
Biotechnology in Medicine
1
-24
Molecular 
Biology
E. 
coli 
information 
and 
decoding 
genetic 
abbreviations
• 
E. 
coli
stats
http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi
• 
E. 
coli
genotypes 
(very 
useful)
http://openwetware.org/wiki/E._coli_genotypes#JM101
• 
Dam 
and 
Dcm 
methylases 
of 
E. 
coli
http://www.neb.com/nebecomm/tech_reference/restriction_enzymes/dam_dcm_methylases_ 
of_ecoli.asp
Nucleic 
acid 
sequences
• 
National 
Center 
for 
Biotechnology 
Information
http://www.ncbi.nlm.nih.gov/ 
• 
European 
Bioinformatics 
Institute
http://www.ebi.ac.uk/ 
• 
Center 
for 
Information 
Biology 
and 
DNA 
Data 
Bank 
of 
Japan
http://www.cib.nig.ac.jp/ 
http://www.ddbj.nig.ac.jp/ 
Nucleic 
acid 
structure
• 
Nucleic 
Acid 
Database
http://ndbserver.rutgers.edu/
Protein 
sequences
• 
Swiss-Prot 
and 
TrEMBL
http://us.expasy.org/sprot/
Protein 
structures
• 
RCSB 
Protein 
Data 
Bank
http://www.rcsb.org/pdb/ 
• 
Swiss-3DImage
http://us.expasy.org/sw3d/
Protein 
families 
and 
domains
• 
Prosite
http://us.expasy.org/prosite/
References 
and 
Recommended 
Further 
Reading
Alberts, 
B., 
Bray, 
D., 
Lewis, 
J., 
Raff, 
M., 
Roberts, 
K., 
and 
Watson, 
J.D. 
Molecular 
Biology 
of 
the 
Cell
. 
Garland 
Publishing, 
New 
York, 
1994.
Dieffenbach, 
C.W. 
and 
Dveksler, 
G.S., 
eds. 
PCR 
Primer: 
A 
Laboratory 
Manual
. 
Cold 
Spring 
Harbor 
Laboratory 
Press, 
Cold 
Spring 
Harbor, 
New 
York, 
2003.
McPherson, 
M.J. 
and 
Møller, 
S.G. 
PCR
. 
BIOS 
Scientic 
Publishers 
Limited, 
Oxford, 
2001.
Stephen, 
A.E., 
Masiakos, 
P.T., 
Segev, 
D.L., 
Vacanti, 
J.P., 
Donahoe, 
P.K., 
and 
MacLaughlin, 
D.T. 
Tissue-
engineered 
cells 
producing 
complex 
recombinant 
proteins 
inhibit 
ovarian 
cancer 
in 
vivo
. 
Proc. 
Natl 
Acad. 
Sci. 
USA
, 
98, 
3214–3219, 
2001.

Table of contents

  1. Front Cover
  2. Contents
  3. Preface
  4. Editors
  5. Contributors
  6. Chapter 1: Historical Perspective and Basics of Molecular Biology
  7. Chapter 2: Biomolecular Interactions
  8. Chapter 3: Recent Advances in DNA Separations: Plasmid Purification, Rapid Electrophoresis, and Affinity-Based Recovery
  9. Chapter 4: Systems and Technology Involving Bacteria
  10. Chapter 5: Expression in Mammalian Cells
  11. Chapter 6: DNA Vaccines Production and Engineering
  12. Chapter 7: Biomimetic Systems: Concepts, Design, and Emulation
  13. Chapter 8: Transport/Reaction Processes in Biology and Medicine
  14. Chapter 9: Microvascular Heat Transfer
  15. Chapter 10: Fluid Dynamics for Bio Systems: Fundamentals and Model Analysis
  16. Chapter 11: Animal Surrogate Systems
  17. Chapter 12: Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease
  18. Chapter 13: Transport Phenomena and the Microenvironment
  19. Chapter 14: Transport and Drug Delivery through the Blood–Brain Barrier and Cerebrospinal Fluid
  20. Chapter 15: Interstitial Transport in the Brain: Principles for Local Drug Delivery
  21. Chapter 16: Surfactant Transport and Fluid–Structure Interactions during Pulmonary Airway Reopening
  22. Chapter 17: Modeling Strategies and Cardiovascular Dynamics
  23. Chapter 18: Compartmental Models of Physiological Systems
  24. Chapter 19: Cardiovascular Models and Control
  25. Chapter 20: Respiratory Models and Control
  26. Chapter 21: Biomimetic Approaches to Physiological Control
  27. Chapter 22: Methods and Tools for Identification of Physiologic Systems
  28. Chapter 23: Modeling Vascular Vibrations: Autoregulation and Vascular Sounds
  29. Chapter 24: External Control of Movements
  30. Chapter 25: The Fast Eye Movement Control System
  31. Chapter 26: A Comparative Approach to Analysis and Modeling of Cardiovascular Function
  32. Chapter 27: A Biomedical and Biophysical Approach to the Science in Cardiopulmonary Resuscitation
  33. Chapter 28: Kinematic Modeling of Left Ventricular Diastolic Function
  34. Chapter 29: Engineering the Pluripotent Stem Cell Niche for Directed Mesoderm Differentiation
  35. Chapter 30: Cell Mechanobiology in Regenerative Medicine: Lessons from Cancer
  36. Chapter 31: Systems-Engineering Principles in Signal Transduction and Cell-Fate Choice
  37. Chapter 32: Biomaterial Scaffolds for Human Embryonic Stem Cell Culture and Differentiation
  38. Chapter 33: Stem Cells and Regenerative Medicine in the Nervous System
  39. Chapter 34: Stem Cells and Regenerative Medicine for Treating Damaged Myocardium
  40. Chapter 35: Stem Cells and Hematopoiesis
  41. Chapter 36: Synthetic Biomaterials and Stem Cells for Connective Tissue Engineering
  42. Chapter 37: Derivation and Expansion of Human Pluripotent Stem Cells
  43. Chapter 38: Bioreactors for Stem Cell Expansion and Differentiation
  44. Chapter 39: Strategic Directions
  45. Chapter 40: Silks
  46. Chapter 41: Calcium Phosphates
  47. Chapter 42: Engineered Protein Biomaterials
  48. Chapter 43: Synthetic Biomaterials
  49. Chapter 44: Growth Factors and Morphogens: Signals for Tissue Engineering
  50. Chapter 45: Signal Expression in Engineered Tissues
  51. Chapter 46: Pluripotent Stem Cells
  52. Chapter 47: Hematopoietic Stem Cells
  53. Chapter 48: Mesenchymal Stem Cells
  54. Chapter 49: Nanobiomaterials for Tissue Engineering
  55. Chapter 50: Biomimetic Approaches in Tissue Engineering
  56. Chapter 51: Molecular Biology Techniques
  57. Chapter 52: Biomaterial Mechanics
  58. Chapter 53: Mechanical Conditioning
  59. Chapter 54: Micropatterned Biomaterials for Cell and Tissue Engineering
  60. Chapter 55: Drug Delivery
  61. Chapter 56: Gene Therapy
  62. Chapter 57: Nanotechnology-Based Cell Engineering Strategies for Tissue Engineering and Regenerative Medicine Applications
  63. Chapter 58: Cell Encapsulation
  64. Chapter 59: Coculture Systems for Mesenchymal Stem Cells
  65. Chapter 60: Tissue Engineering Bioreactors
  66. Chapter 61: Shear Forces
  67. Chapter 62: Vascularization of Engineered Tissues
  68. Chapter 63: Biomedical Imaging of Engineered Tissues
  69. Chapter 64: Multiscale Modeling of In Vitro Tissue Cultivation
  70. Chapter 65: Bone Engineering
  71. Chapter 66: Dental and Craniofacial Bioengineering
  72. Chapter 67: Tendon and Ligament Engineering
  73. Chapter 68: Cartilage Tissue Engineering
  74. Chapter 69: TMJ Engineering
  75. Chapter 70: Interface Tissue Engineering
  76. Chapter 71: The Bioengineering of Dental Tissues
  77. Chapter 72: Tissue Engineering of the Urogenital System
  78. Chapter 73: Vascular Tissue Engineering
  79. Chapter 74: Neural Engineering
  80. Chapter 75: Tumor Engineering: Applications for Cancer Biology and Drug Development
  81. Chapter 76: Artificial Heart and Circulatory Assist Devices
  82. Chapter 77: Cardiac Valve Prostheses
  83. Chapter 78: Artificial Lungs
  84. Chapter 79: Blood Substitutes
  85. Chapter 80: Liver Support Systems
  86. Chapter 81: Peritoneal Dialysis Equipment
  87. Chapter 82: Artificial Skin and Dermal Equivalents
  88. Chapter 83: Physiological Barriers to Drug Transport
  89. Chapter 84: Nucleic Acid Aptamers in Drug Delivery
  90. Chapter 85: Dendrimers for Drug Delivery
  91. Chapter 86: Noninvasive Targeted Protein and Peptide Drug Delivery
  92. Chapter 87: Environment-Responsive Hydrogels for Drug Delivery
  93. Chapter 88: Biodegradable PLGA Scaffolds for Growth Factor Delivery
  94. Chapter 89: Physiogenomic Contours: The Application of Systems Biology for Engineering Personalized Healthcare
  95. Chapter 90: The Evolution of Massively Parallel Sequencing Technologies: Facilitating Advances in Personalized Medicine
  96. Chapter 91: Computational Methods and Molecular Diagnostics in Personalized Medicine
  97. Chapter 92: Need for Point-of-Care Testing Devices for Cardiac Troponin in Patients with Acute Coronary Syndromes
  98. Chapter 93: An Introduction to Bioethics and Ethical Theory for Biomedical Engineers*
  99. Back Cover