Glutamine
eBook - ePub

Glutamine

Biochemistry, Physiology, and Clinical Applications

  1. 386 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Glutamine

Biochemistry, Physiology, and Clinical Applications

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About This Book

Glutamine: Biochemistry, Physiology, and Clinical Applications describes the different functions of glutamine (Gln) in animals and humans. Gln is both a nutrient and a signaling molecule, and its functions go beyond those of a simple metabolic fuel or protein precursor. This book has gathered together, in an unbiased and critical manner, all the available evidence and research on Gln including pathology (neurological diseases, intestinal diseases, critical illness, and cancer), physiology (successful aging), catabolic states, immunity, and exercise. Special attention is given to the potential benefit of Gln in states of insulin resistance and the role of Gln as a "conditionally essential" amino acid.

The contributors are either pioneers or experts in the area of Gln from all around the globe, including Australia, Brazil, Canada, Europe, China, and the United States. This book is a valuable source of information for nutrition scientists, medical doctors, sports scientists, food scientists, dietitians, and anyone interested in nutrition. It is also a valuable resource for students in these fields and will be an important addition to university libraries.

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Yes, you can access Glutamine by Dominique Meynial-Denis in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2017
ISBN
9781315355832
Edition
1
Topic
Medicine
Subtopic
Biochemistry in Medicine

Index

A
Acquired immunity, 294–295; see also Immune system
Acute kidney injury (AKI), 244, 245, 369; see also Glutamine supplementation in critical illness
septic and nonseptic, 245–247
toxic effects of glutamine, 251
Acute liver failure (ALF), 111; see also Brain glutamine
Acute Physiological and Chronic Health Evaluation (APACHE), 201, 208
Acute uremia, 246
Adenomatous polyposis coli (APC), 87
Adenosine monophosphate (AMP), 317
Adenosine triphosphate (ATP), 84, 296
AG, see Alanyl-glutamine
Aging, 348; see also Glutamine metabolism; Glutamine supplementation in old age
autophagy, 350
effect on glutamine metabolism 350–351, 352–353, 356–357
effect on glutamine synthesis, 353, 355–356
effect on interorgan glutamine flow, 356
glutamine and glutamate fluxes, 354
glutamine and protein turnover, 351–352
glutaminolysis, 356
physical activity vs. inactivity, 352
and protein turnover in skeletal muscle, 352
protein wasting, 351
sarcopenia, 348
Schlafen 3, 355
AKGM, see Alpha-ketoglutaramate
AKI, see Acute kidney injury
Alanine transaminase (ALT), 283
Alanyl-glutamine (AG), 56
ALF, see Acute liver failure
Alpha-(methylamino)-isobutyric acid (MeAIB), 267
Alpha-ketoglutaramate (AKGM), 116
ALT, see Alanine transaminase
Alzheimer type 2 astrocytosis, 111; see also Brain glutamine
Ammoniagenesis, 263
Ammonia scavenger system, 261; see also Cancer glutamine metabolism
AMP, see Adenosine monophosphate
AMP-activated protein kinase (AMPK), 72
AMPK, see AMP-activated protein kinase
anti-18F-FACBC, see trans-1-amino-3–18F-fluorocyclob utanecarboxylic acid
Antibodies, 294–295
Antigen, 295; see also Immune system
Antigen presenting cell (APC), 295
Antioxidant cocktail, 215; see also Glutamine oxidative injury pathways
APACHE, see Acute Physiological and Chronic Health Evaluation
APC, see Adenomatous polyposis coli; Antigen presenting cell
APChomo mice, 87
Apoptotic signaling mechanisms, 349; see also Glutamine metabolism
Arginine, 188
Glutamine dip...

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Dedication Page
  5. Table of Contents
  6. Preface
  7. Editor
  8. Contributors
  9. Introduction: The Magic of a Marvelous Amino Acid—Glutamine
  10. SECTION I Basics of Glutamine Metabolism
  11. SECTION II New Data on the Biochemistry of Glutamine
  12. SECTION III Molecular and Cellular Aspects of Glutamine Metabolism
  13. SECTION IV Glutamine, the Brain and Neurological Diseases
  14. SECTION V Glutamine and the Intestinal Tract
  15. SECTION VI Glutamine and the Catabolic State: Role of Glutamine in Critical Illness During Childhood
  16. SECTION VII Glutamine and the Catabolic State: Role of Glutamine in Critical Illness from Adulthood
  17. SECTION VIII Glutamine and the Catabolic State: Role of Glutamine in Cancer
  18. SECTION IX Glutamine, Immunity, and Exercise
  19. SECTION X Glutamine and Aging
  20. SECTION XI Conclusion
  21. Index