Acute Coronary Syndromes

K Sarat Chandra, AJ Swamy, K Sarat Chandra, AJ Swamy

• Publisher: CRC Press
• Year: 2020
• ISBN:
  9780429655555
• Edition: 1
• Topic: Medicine
• Subtopic: Medical Theory, Practice & Reference

Acute Coronary Syndrome (ACS) is a growing global menace with patients increasing in developing countries where tobacco and food play a major role. Its treatment guidelines and research results have proliferated in academia, but practical applications lag behind that research. This book addresses this void. Guidelines for treatment of ACS present in-depth reading for practicing cardiologists, thus preventing clinical application. The book aims to appraise readers of real-world situations and suggestions to help them acquire up-to-date knowledge on ACS and its effective diagnosis, prognosis and management.

Key Features

• Covers recent advances in ACS management and pharmacotherapy

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• Discusses the guidelines for treatment of ACS for the professional cardiologist to apply to clinical practice

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• Explores the topics with the help of case scenarios

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• Follows a concise, yet comprehensive approach

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• Features a chapter on 'When to Transfer, ' which discusses how to spot unstable patients or those heading towards shock

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1

Epidemiology of acute coronary syndromes in India

Rajeev Gupta and Kiran Gaur

India: Coronary capital of the world

Acute coronary syndromes in India

Geographic epidemiology

Clinical and pharmacoepidemiology

Genetic epidemiology

Conclusion

References

India: Coronary capital of the world

Cardiovascular diseases, especially coronary or ischaemic heart disease (IHD), are epidemics in India [1]. A decade ago, it was predicted that by the year 2020 India would gain the dubious distinction of being the coronary capital of the world [2]. Perusal of the current data from the Global Burden of Disease (GBD) Study and others shows that this prediction has already come true. The Registrar General of India has reported that mortality from cardiovascular diseases is rapidly increasing in the country [3]. The World Health Organization (WHO) and the Global Burden of Disease (GBD) Study have highlighted secular increase in mortality, years of life lost (YLLs) and disability-adjusted life years (DALYs) from IHD in India [4,5]. In India, studies have reported increasing coronary heart disease (CHD) prevalence over the last 60 years, from 1% to 9%–10% in urban populations and from <1% to 4%–6% in rural populations [6–8]. Using more stringent criteria (clinical diagnosis and/or Q waves), the current prevalence varies from 1% to 2% in rural populations and 2%–4% in urban populations [1]. All these calculations were based on limited data using a small number of regional studies. The Million Death Study in India has been using the Indian Sample Registration System data and verbal autopsy to assess causes of death in different states of the country since the year 2003 [9,10]. For the last two decades the GBD group and others have been systematically collating IHD morbidity and mortality data, globally and in India, from various sources to produce estimates of nationwide and state-specific IHD burden in the country [11,12].

The GBD Study has reported an annual absolute burden of IHD mortality and DALYs as well as rates per 100,000 persons in more than 190 countries. To compare the total mortality and death rates from IHD as well as disease burde...

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Dedication
• Contents
• Foreword
• Preface
• Acknowledgements
• Editors
• Contributors
• 1. Epidemiology of acute coronary syndromes in India
• 2. Pathophysiology of acute coronary syndrome
• 3. Current outcomes and outcome measures in acute coronary syndrome
• 4. Clinical syndromes in acute coronary syndrome: Angina and its equivalents
• 5. ECG spectrum in acute coronary syndrome
• 6. Arrhythmias in acute coronary syndrome
• 7. Intravascular imaging in acute coronary syndrome
• 8. Cardiac biomarkers in acute coronary syndrome
• 9. Risk stratification in acute coronary syndromes
• 10. Initial therapy and when to transfer at non-pci centres
• 11. Anti-platelet therapy in acute coronary syndrome: What is current and new?
• 12. Current status of fibrinolytic therapy
• 13. Anti-coagulation in acute coronary syndrome
• 14. Contentious issues in primary angioplasty: Deferred stenting, manual thrombectomy, culprit versus complete revascularisation, microvasculature in ACS
• 15. PCI post-thrombolysis: When and for whom?
• 16. PCI in unstable angina and NSTEMI
• 17. Bleeding in acute coronary syndrome
• 18. Statins in acute coronary syndrome
• 19. Intravenous anti-platelet therapy—GP IIb/IIIa blockers and cangrelor: What has changed recently?
• 20. CABG in acute coronary syndrome
• 21. Acute coronary syndrome with haemodynamic instability
• 22. Acute coronary syndrome in special populations: Women, the elderly, chronic kidney disease and the young
• 23. Short-term rehabilitation after an acute coronary event
• 24. Acute coronary syndrome: Case-based scenarios
• 25. Quality improvement programme for acute coronary syndrome care in India
• 26. Primary angioplasty: Basic principles
• 27. Management of acute coronary syndromes in acute phase in India: Relevance of Western guidelines
• Index