Obesity
eBook - PDF

Obesity

Genomics and Postgenomics

  1. 600 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Obesity

Genomics and Postgenomics

Book details
Table of contents
Citations

About This Book

This book comprehensively accounts the current understanding of genetic mechanisms of obesity by analyzing obesity phenotypes and genotypes and, gene polymorphisms and mutations, and current results from animal model research and genetic studies in human models. By presenting the impact of genetic factors in the development of obesity and key molec

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Yes, you can access Obesity by Karine Clement, Thorkild I. A. Sorensen in PDF and/or ePUB format, as well as other popular books in Medicine & Medical Theory, Practice & Reference. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2007
ISBN
9781420020137

Table of contents

  1. Front cover
  2. Preface
  3. Contents
  4. Contributors
  5. Introduction
  6. Section 1: Obesity Phenotype
  7. Chapter 1.1 Human Phenotypes
  8. Section 2: Quantitative Genetics of Obesity
  9. Chapter 2.1 Family Studies
  10. Chapter 2.2 Adoption Studies
  11. Chapter 2.3 Twin Studies
  12. Chapter 2.4 Experimental Twin Studies
  13. Chapter 2.5 Commingling and Segregation Analyses
  14. Section 3: Rodent Models of Obesity
  15. Chapter 3.1 Natural Monogenic Models
  16. Chapter 3.2 Transgenic Models Targeting the Central Nervous System
  17. Chapter 3.3 Transgenic Models in the Periphery
  18. Chapter 3.2 Natural Polygenic Models
  19. Section 4: Nonvertebrate Models
  20. Chapter 4.1 Will Fatty Worms or Flies Help Discover the Mechanism of Human Obesity?
  21. Section 5: Syndromic and Monogenic Human Obesity
  22. Chapter 5.1 Overview of Human Monogenic, Nonsyndromic, and Syndromic Obesity
  23. Chapter 5.2 Prader-Willi Syndrome
  24. Chapter 5.3 Bardet-Biedl Syndrome: New Insights into Ciliopathies and Oligogenic Traits
  25. Chapter 5.4 Leptin and Leptin Receptor Mutations
  26. Chapter 5.5 POMC and PC1 Mutations
  27. Chapter 5.6 MC4R Mutations
  28. Section 6: Polygenic Human Obesity
  29. Chapter 6.1 Overview of Genetic Studies in Polygenic Obesity and Methodological Challenges
  30. Chapter 6.2 Genome-Wide Approaches
  31. Chapter 6.3 Association and Linkage Studies in Caucasians
  32. Section 7: Gene-Environment Interaction in Human Obesity
  33. Chapter 7.1 Genetics of Eating Behavior
  34. Chapter 7.2 Genetics of Physical Activity
  35. Chapter 7.3 Interaction Between Genes and Lifestyle Factors
  36. Chapter 7.4 Genetics and Hormonal Changes
  37. Chapter 7.5 Genetics and Drugs
  38. Section 8: Epigenetics in Obesity
  39. Chapter 8.1 Molecular Basis of Epigenetic Memory
  40. Chapter 8.2 Implications for Obesity and Common Diseases
  41. Section 9: Tissue and Organ-Specific Gene Function
  42. Chapter 9.1 Genes Regulating Adipose-Tissue Development and Function
  43. Chapter 9.2 Genetics of Adipose-Tissue Development and Function in Humans
  44. Chapter 9.3 Nutritional Regulation of Adipocyte Differentiation
  45. Chapter 9.4 Genes Involved in Muscle Function
  46. Chapter 9.5 Genes Involved in Gut and Brain Dialogue
  47. Section 10: Omics Technology and System Biology
  48. Chapter 10.1 Introduction to Omics Platforms
  49. Chapter 10.2 Analysis and Data Integration
  50. Chapter 10.3 Transcriptomics Results
  51. Chapter 10.4 Proteomics and Metabonomics Routes Toward Obesity
  52. Chapter 10.5 Quantitative Proteomics for Analysis of Adipocyte Development and Function
  53. Section 11: Conclusion
  54. Chapter 11.1 Exciting Advances and New Opportunities
  55. Index
  56. Back cover