PARP as a Therapeutic Target
eBook - PDF

PARP as a Therapeutic Target

  1. 360 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

PARP as a Therapeutic Target

Book details
Table of contents
Citations

About This Book

Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati

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Yes, you can access PARP as a Therapeutic Target by Jei Zhang, Jei Zhang in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2002
ISBN
9781420042405
Edition
1
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Cover
  2. Foreword
  3. Preface
  4. The Editor
  5. Table of Contents
  6. 1. Nervous System Functions of Poly (ADP-Ribose) Polymerase-1
  7. 2. Role of Poly (ADP-Ribose) Polymerase-1 in Neurologic Disorders
  8. 3. Involvement of PARP-1 and Poly (ADP-Ribosyl)ation in the Maintenance of Genomic Stability
  9. 4. Functional Testing of Human PARP in Proliferation, EndotoxicShock, and Radiosensitivity: A Genetic Rescue Study
  10. 5. PARP Inhibitors as Neuroprotective Agents for Brain Injury
  11. 6. PARP Inhibitors and Cardioprotection
  12. 7. Neuroprotection of the Retina with 3-Aminobenzamide, a PARP Inhibitor
  13. 8. Poly (ADP-Ribose) Polymerase Inhibitors and Acute Renal Failure
  14. 9. Role of Poly (ADP-Ribose) Polymerase Activation in the Pathogenesis of Shock and Inflammation
  15. 10. Clinical Development of the Nicotinamides and Benzamides Involving PARP as a Molecular Target
  16. 11. Chemoprotective Effect of a Novel PARP Inhibitor
  17. 12. Beneficial Effect of GPI 6150 Treatment in Multiple Animal Models of Diseases
  18. 13. Protecting Effect of PARP Inhibition on Ultraviolet Light–Induced Skin Damage
  19. 14. Role of Poly (ADP-Ribose) Polymerase Activation in the Pathogenesis of Diabetes Mellitus and Diabetic Vascular Dysfunction
  20. 15. Therapeutic Targeting of the PARPs: Future Challenges, Future Opportunities
  21. Index