Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies
- 240 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies
About This Book
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells.
From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.
- Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding
- Updates current trends in the field with pioneering information on drug resistance
- Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view
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Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Aims and Scope for Series âCancer Sensitizing Agents for Chemotherapyâ
- About the Series Editor
- Aims and Scope of the Volume
- About the Editors
- Preface
- Contributors
- Chapter 1: Drug resistance in colorectal cancer: General aspects
- Chapter 2: Drug transporters in the development of multidrug resistance in colorectal cancer
- Chapter 3: Role of colorectal cancer stem cells in resistance to apoptosis and treatment in colorectal cancer
- Chapter 4: Serrated lesions and stem cells on drug resistance and colon cancer
- Chapter 5: Development of novel microRNA-based therapeutics platform for colorectal cancer
- Chapter 6: Chemo-sensitizing agents from natural origin for colorectal cancer: Pharmacodynamic and cellular pharmacokinetics approaches
- Chapter 7: Induction of programmed necrosis by phytochemicals in colorectal cancer
- Chapter 8: Predictive biomarkers of drug resistance in colorectal cancerâRecent updates
- Chapter 9: Rac1b: An emerging therapeutic target for chemoresistance in colorectal cancer
- Chapter 10: Nanotechnology-based targeted drug delivery systems and drug resistance in colorectal cancer
- Chapter 11: Targeting colorectal cancer via nanodrug delivery systems
- Index