- 792 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
About This Book
The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation.
This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness.
Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers!
- 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers
- Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness
- Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease
- Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself
- Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols
Frequently asked questions
Information
Normal and Variant Sex Development
Abstract
Keywords
1.1 Physiology of Biological Sex Development
1.1.1 Background
1.1.2 Chromosomal Sex
1.1.3 Gonadal Sex
1.1.3.1 Sex Differentiation and Somatic Sex
Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Praise for Principles of Gender-Specific Medicine, 3rd edition
- List of Contributors
- Foreword
- Preface
- Chapter 1. Normal and Variant Sex Development
- Chapter 2. Gender Diagnoses
- Chapter 3. Gender Identity in Disorders of Sex Development
- Chapter 4. Female Sexual Function: The Role of Animal Models in Assessing Female Sexual Dysfunction
- Chapter 5. Fertility Treatment and Preservation in Transgender Men and Women
- Chapter 6. Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People: An Introduction
- Chapter 7. Sex-Dependent and -Independent Mechanisms in External Genitalia Development
- Chapter 8. The Transsexual Adult
- Chapter 9. Sexual and Gender Minority Individuals in Health Care: Strategies to Include Sexual Orientation and Gender Identity in Health Professions Education
- Chapter 10. Sex Influences Exist at All Levels of Human Brain Function
- Chapter 11. Sex Differences in the Brain: Focus on Developmental Mechanisms
- Chapter 12. Sexual Dimorphisms in the Nervous System of the Nematode Caenorhabditis elegans
- Chapter 13. Oxytocin and Brain Plasticity
- Chapter 14. Emotion and Gender-Specific Neural Processing in Men and Women
- Chapter 15. Behind the Mask: The Experience of Assessment, Diagnosis, and Living with Autism for Girls and Young Women
- Chapter 16. The Significance of Gender in Perinatal Medicine
- Chapter 17. Intrauterine Development of Sex DifferencesâFetal Programming
- Chapter 18. Battle of the Sexes: How the Selection of Spermatozoa in the Female Reproductive Tract Manipulates the Sex Ratio of Offspring
- Chapter 19. All Cells Have a Sex: Studies of Sex Chromosome Function at the Cellular Level
- Chapter 20. Sex-Specific Implications of Exposure to An Adverse Intrauterine Environment
- Chapter 21. Immune ResponseâThe Impact of Biological Sex and Gender
- Chapter 22. Geoepidemiology and the Impact of Sex on Autoimmune Diseases
- Chapter 23. Gender and Gene Regulation in Human Immunity
- Chapter 24. Sex and Gender Specific AspectsâFrom Cells to Cardiovascular Disease
- Chapter 25. Estrogen: Impact on Cardiomyocytes and the Heart
- Chapter 26. The Sexually Dimorphic Characteristics of the Pathophysiology and Treatment of Atrial Fibrillation
- Chapter 27. Gender Differences in Chronic Obstructive Pulmonary DiseaseâCurrent Knowledge and Deficits
- Chapter 28. Cancer: Gender Differences at the Molecular Level
- Chapter 29. An Updated Overview of the Gender-Specific Response to Infection
- Chapter 30. Gender-Based Differences in Mortality in Indian Children Aged 5 to 14 years
- Chapter 31. Consideration of Biological Sex in Translating Regenerative Stem Cell Therapies
- Chapter 32. Adipose-Derived Stem Cells in Regenerative Medicine
- Chapter 33. Sex, Gender, and Pain
- Chapter 34. Sex and Gender Differences in Trauma Victims Presenting for Treatment
- Chapter 35. Women Do Worse Than MenâGender-Specific Differences in Burn Patients
- Chapter 36. Exercise Physiology in Men and Women
- Chapter 37. Musculoskeletal Complaints in Male and Female Instrumental Musicians
- Chapter 38. Nutritional Genomics and Biological Sex
- Chapter 39. Microbiome: Impact of Gender on Function & Characteristics of Gut Microbiome
- Chapter 40. Sex and Gender Differences in Sleep Disorders: An Overview
- Chapter 41. Gender Differences in Bladder and Kidney Cancers
- Chapter 42. The Complex Challenge of Blood Pressure Regulation: Influences of Sex and Aging on Sympathetic Mechanisms
- Chapter 43. Gender at the Interface of Renal Aging: Physiological and Pathological Perspectives
- Chapter 44. Gender Differences in Mobility of Elderly: Measurements and Interventions to Improve Mobility
- Chapter 45. Personalized Medicine in Space Flight, Part I: Standard Clinical Approaches
- Chapter 46. Personalized Medicine in Space Flight, Part II: Personalized Precision Medicine Approaches
- Chapter 47. Robots and Gender
- Chapter 48. Cyborgs: Understanding and Mutual Treatment
- Chapter 49. Precision Medicine and Challenges in Research and Clinical Implementation
- Chapter 50. Gender-Specific Medicine in Pharmaceutical Drug Discovery and Development
- Index