Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine.

While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers.

The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.

The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research.

Uses individual drugs to explain molecular actions
Full color art program explains molecular and chemical concepts graphically
Logical structure reflecting the current state of pharmacology and translational research
Covers such intricacies as drug resistance and cell death
Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Frequently asked questions

Simply head over to the account section in settings and click on “Cancel Subscription” - it’s as simple as that. After you cancel, your membership will stay active for the remainder of the time you’ve paid for. Learn more here.

At the moment all of our mobile-responsive ePub books are available to download via the app. Most of our PDFs are also available to download and we're working on making the final remaining ones downloadable now. Learn more here.

Both plans give you full access to the library and all of Perlego’s features. The only differences are the price and subscription period: With the annual plan you’ll save around 30% compared to 12 months on the monthly plan.

We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.

Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.

Yes, you can access Pharmacology by Miles Hacker,William S. Messer,Kenneth A. Bachmann in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Academic Press

Year

2009

ISBN

9780080919225

Topic

Medicine

Subtopic

Pharmacology

Cover Image
Table of Contents
Copyright
Dedication
Contributors
Preface
Chapter 1. History of Pharmacology—From Antiquity to the Twentieth Century
Chapter 2. Dosage Forms and Their Routes of Administration
Chapter 3. Membranes and Drug Action
Chapter 4. Ligand-Receptor Binding and Tissue Response
Chapter 5. Hormesis and Pharmacology
Chapter 6. Signal Transduction and Second Messengers
Chapter 7. Drug Distribution
Chapter 8. Drug Metabolism
Chapter 9. Drug Excretion
Chapter 10. Pharmacokinetic Modeling
10.1. Introduction
10.2. Chemical Transport
10.3. Absorption
10.4. Distribution
10.5. Elimination (Metabolism and Excretion)
10.6. Organization of Single-Dose Pharmacokinetic Model Information
10.7. One-Compartment Bolus IV Injection (Instantaneous Absorption) Model
10.7.4. Estimating Model Parameters from Measured Plasma Concentration Data
10.7.5. Special Cases of the One-Compartment Bolus IV (Instantaneous Absorption) Model
10.8. One-Compartment IV Infusion (Zero-Order Absorption) Model
10.9. One-Compartment First-Order Absorption Model
10.10. Two-Compartment Bolus IV Injection (Instantaneous Absorption) Model
10.11. Two-Compartment IV Infusion (Zero-Order Absorption) Model
10.12. Two-Compartment First-Order Absorption Model
10.13. Generalized Multicompartment Models
10.14. Multiple Dosing Models
10.15. Advanced Pharmacokinetic Modeling Topics
10.16. Summary of Key Points
Chapter 11. Bioanalytical Tools for Drug Analysis
Chapter 12. Drug–Drug Interactions with an Emphasis on Drug Metabolism and Transport
Chapter 13. Adverse Drug Reactions
Chapter 14. Risk Assessment
Chapter 15. Drug Resistance
Chapter 16. Ion Channels
Chapter 17. Targeting the Cell Cycle to Kill Cancer Cells
Chapter 18. Programmed Cell Death
Chapter 19. Drug Discovery
19.1. Introduction
19.2. Underlying Principles
19.3. Drug Discovery Case Studies
19.4. Summary
Chapter 20. Genomics and Proteomics in Drug Design and Discovery
Chapter 21. The Future of Pharmacology
Index