Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
- 960 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
About This Book
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients
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Table of contents
- Cover image
- Title page
- Table of Contents
- Acknowledgement
- Preface
- Chapter 1: Introduction
- Chapter 2: Integumentary System
- Chapter 3: Mammary Gland
- Chapter 4: Haemopoietic and Lymphatic Systems
- Chapter 5: Musculoskeletal System
- Chapter 6: Respiratory Tract
- Chapter 7: Cardiovascular System
- Chapter 8: Digestive System
- Chapter 9: Liver and Pancreas
- Chapter 10: Urinary Tract
- Chapter 11: Male Genital Tract
- Chapter 12: Female Genital Tract
- Chapter 13: Endocrine Glands
- Chapter 14: Nervous System and Special Sense Organs
- Subject Index