Essential Bioimaging Methods

P. Michael Conn

• Publisher: Academic Press
• Year: 2009
• Print ISBN: 9780123750433
• eBook ISBN: 9780080963426
• Topic: Medicine
• Subtopic: Neurology

Need a tested, reliable method that works? Put Essential Bioimaging Methods to work for you. Editor Michael Conn has hand-picked the most robust methods from his previously-published volumes in the Methods in Enzymology series. Many of these methods have been briefly updated by the authors that created them and use them in their research, and this book further refines and organizes existing content and focuses on methods that work, including MRI, fMRI, PET, Microscopic optical imaging and other. Part of the Reliable Lab Solution series, this volume provides clear advice and explicit protocols, providing updates to classic, tried-and-true methods and an essential addition to the bookshelf or workbench of any researcher in the field. * Highlights usefulness of techniques in basic research detailing MRI imaging of small animals, fMRI of Macaque monkeys, and baboon model of reperfused stroke * Built from volumes in the flagship brand, Methods in Enzymology* Provides tricks, tips and different approaches

Table of contents

• Cover Image
• Table of Contents
• Copyright
• Contributors
• Preface
• Chapter 1. Positron Emission Tomography (PET)
• Chapter 2. Biophysical Basis of Magnetic Resonance Imaging of Small Animals
• Chapter 3. Functional Magnetic Resonance Imaging of Macaque Monkeys
• Chapter 4. Atlas Template Images for Nonhuman Primate Neuroimaging
• Chapter 5. Magnetic Resonance Imaging of Brain Function
• Chapter 6. Positron Emission Tomography Receptor Assay with Multiple Ligand Concentrations
• Chapter 7. Estimation of Local Receptor Density, Bmax′, and Other Parameters via Multiple-Injection Positron Emission Tomography Experiments
• Chapter 8. Magnetic Resonance Imaging in Biomedical Research
• Chapter 9. Imaging Myocardium Enzymatic Pathways with Carbon-11 Radiotracers
• Chapter 10. Molecular and Functional Imaging of Cancer
• Chapter 11. A Modified Transorbital Baboon Model of Reperfused Stroke
• Chapter 12. Structural and Functional Optical Imaging of Angiogenesis in Animal Models
• Chapter 13. MRI of Animal Models of Brain Disease
• Chapter 14. Magnetic Resonance Imaging in Animal Models of Pathologies
• Chapter 15. Application of Combined Magnetic Resonance Imaging and Histopathologic and Functional Studies for Evaluation of Aminoguanidine Following Traumatic Brain Injury in Rats
• Chapter 16. Vascular-Targeted Nanoparticles for Molecular Imaging and Therapy
• Chapter 17. Generation of DOTA-Conjugated Antibody Fragments for Radioimmunoimaging
• Chapter 18. The Application of Magnetic Resonance Imaging and Spectroscopy to Gene Therapy
• Chapter 19. Voxelation Methods for Genome Scale Imaging of Brain Gene Expression
• Index