- 656 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
About this book
Research on dyneins has a direct impact on human diseases, such as viruses and cancer. With an accompanying website showing over 100 streaming videos of cell dynamic behavior for best comprehension of material, Dynein: Structure, Biology and Disease is the only reference covering the structure, biology and application of dynein research to human disease. From bench to bedside, Dynein: Structure, Biology and Disease offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics and medicine.
- Broad-based up-to-date resource for the dynein class of molecular motors
- Chapters written by world experts in their topics
- Numerous well-illustrated figures and tables included to complement the text, imparting comprehensive information on dynein composition, interactions, and other fundamental features
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Table of contents
- Cover image
- Table of Contents
- FrontMatter
- Copyright
- List of Contributors
- Preface
- 1. Discovery of Dynein and its Properties
- 1.1. Introduction
- 1.2. Research at Harvard
- 1.3. Research at the University of Hawaii
- 1.4. Semi-Retirement in Berkeley
- 1.5. The Pluses of Working on a Minus-End-Directed Motor
- 1.6. Epilogue
- 2. Evolutionary Biology of Dyneins
- 3. The AAA+ Powerhouse – Trying to Understand How it Works
- 4. Dynein Motor Mechanisms
- 5. Structural Analysis of Dynein Intermediate and Light Chains
- 6. Biophysics of Dynein In Vivo
- 7. Composition and Assembly of Axonemal Dyneins
- 8. Organization of Dyneins in the Axoneme
- 9. Genetic Approaches to Axonemal Dynein Function in Chlamydomonas and Other Organisms
- 10. Regulation of Axonemal Outer-Arm Dyneins in Cilia
- 11. Control of Axonemal Inner Dynein Arms
- 12. Flagellar Motility and the Dynein Regulatory Complex
- 13. Regulation of Dynein in Ciliary and Flagellar Movement
- 14. Dynein and Intraflagellar Transport
- 15. Cytoplasmic Dynein Function Defined by Subunit Composition
- 16. Studies of Lissencephaly and Neurodegenerative Disease Reveal Novel Aspects of Cytoplasmic Dynein Regulation
- 17. Insights into Cytoplasmic Dynein Function and Regulation from Fungal Genetics
- 18. Genetic Insights into Mammalian Cytoplasmic Dynein Function Provided by Novel Mutations in the Mouse
- 19. The Role of Dynactin in Dynein-Mediated Motility
- 20. Roles of Cytoplasmic Dynein During Mitosis
- 21. Does Dynein Influence the Non-Mendelian Inheritance of Chromosome 17 Homologs in Male Mice?
- 22. Role of Dynein in Viral Pathogenesis
- 23. Cytoplasmic Dynein Dysfunction and Neurodegenerative Disease
- 24. Dynein Dysfunction as a Cause of Primary Ciliary Dyskinesia and Other Ciliopathies
- Index
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Yes, you can access Dyneins by Stephen M. King in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Cell Biology. We have over 1.5 million books available in our catalogue for you to explore.