Eukaryotic Cell Genetics
eBook - PDF

Eukaryotic Cell Genetics

John Morrow

  1. 276 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Eukaryotic Cell Genetics

John Morrow

Book details
Table of contents
Citations

About This Book

Eukaryotic Cell Genetics reviews the state of knowledge in somatic cell genetics. The book begins by discussing the development of somatic cell genetics, focusing on the estimation of mutation rates in mammalian cells, with frequent reference to the use of drug resistance as a selective character. It then considers some of the specific properties of such variants in order to understand their molecular basis. The subsequent chapters examine the properties of specific types of auxotrophic variants; the means by which eukaryotic cells may be reassembled to give rise to viable cellular composites; gene regulation in eukaryotic organisms; and chromosome mapping. The discussions also include differentiation in cultured cells; neoplastic transformation; the modulation of gene expression in cultured cells; mutation induction in cultured cells; applications of cell culture; and the mechanism of cellular aging. This book is intended for researchers in the fields of genetics and molecular biology, nonspecialists interested in what is happening in a very exciting area of biology, and students at the graduate level in cell biology.

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Information

Year
2012
ISBN
9780323158183

Table of contents

  1. Front Cover
  2. Eukaryotic Cell Genetics
  3. Copyright Page
  4. Table of Contents
  5. PREFACE
  6. Chapter 1. Somatic Cell Genetics and the Legacy of Microbial Systems
  7. Chapter 2. Drug Resistance and Its Genetic Basis
  8. Chapter 3. Auxotrophic Variants in Cultured Cells
  9. Chapter 4. Mechanisms for the Exchange of Genetic Information in Cultured Cells
  10. Chapter 5. The Regulation of Gene Expression in Heterokaryons
  11. Chapter 6. Chromosome Mapping
  12. Chapter 7. Differentiation in Cultured Cells: Liver Cells
  13. Chapter 8. Differentiation in Cultured Cells: Muscle Cells, Melanoma Cells, Neuronal Cells, and Hemoglobin-Producing Cells
  14. Chapter 9. Differentiation in Cultured Cells: Cells of the Immune System
  15. Chapter 10. Hypotheses of Malignancy and Their Analysis through the Use of Somatic Cell Hybrids
  16. Chapter 11. Modulation of Gene Expression in Cultured Cells
  17. Chapter 12. Mutation Induction in Cultured Cells
  18. Chapter 13. Use of Cell Culture in the Analysis of Human Heredity
  19. Chapter 14. The Cellular Basis of the Aging Process
  20. Chapter 15. Future Outlook
  21. Bibliography
  22. INDEX