Eukaryotic Cell Genetics
John Morrow
- 276 pages
- English
- PDF
- Available on iOS & Android
Eukaryotic Cell Genetics
John Morrow
About This Book
Eukaryotic Cell Genetics reviews the state of knowledge in somatic cell genetics. The book begins by discussing the development of somatic cell genetics, focusing on the estimation of mutation rates in mammalian cells, with frequent reference to the use of drug resistance as a selective character. It then considers some of the specific properties of such variants in order to understand their molecular basis. The subsequent chapters examine the properties of specific types of auxotrophic variants; the means by which eukaryotic cells may be reassembled to give rise to viable cellular composites; gene regulation in eukaryotic organisms; and chromosome mapping. The discussions also include differentiation in cultured cells; neoplastic transformation; the modulation of gene expression in cultured cells; mutation induction in cultured cells; applications of cell culture; and the mechanism of cellular aging. This book is intended for researchers in the fields of genetics and molecular biology, nonspecialists interested in what is happening in a very exciting area of biology, and students at the graduate level in cell biology.
Frequently asked questions
Information
Table of contents
- Front Cover
- Eukaryotic Cell Genetics
- Copyright Page
- Table of Contents
- PREFACE
- Chapter 1. Somatic Cell Genetics and the Legacy of Microbial Systems
- Chapter 2. Drug Resistance and Its Genetic Basis
- Chapter 3. Auxotrophic Variants in Cultured Cells
- Chapter 4. Mechanisms for the Exchange of Genetic Information in Cultured Cells
- Chapter 5. The Regulation of Gene Expression in Heterokaryons
- Chapter 6. Chromosome Mapping
- Chapter 7. Differentiation in Cultured Cells: Liver Cells
- Chapter 8. Differentiation in Cultured Cells: Muscle Cells, Melanoma Cells, Neuronal Cells, and Hemoglobin-Producing Cells
- Chapter 9. Differentiation in Cultured Cells: Cells of the Immune System
- Chapter 10. Hypotheses of Malignancy and Their Analysis through the Use of Somatic Cell Hybrids
- Chapter 11. Modulation of Gene Expression in Cultured Cells
- Chapter 12. Mutation Induction in Cultured Cells
- Chapter 13. Use of Cell Culture in the Analysis of Human Heredity
- Chapter 14. The Cellular Basis of the Aging Process
- Chapter 15. Future Outlook
- Bibliography
- INDEX