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- 389 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Proteasomes: The World of Regulatory Proteolysis
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About This Book
This book highlights proteasome structures and how they are related to different aspects of proteasome function. Moreover, the book reports on the functional roles these highly developed proteolytic machines play within the cell. It was a great surprise to the scientific world that proteolysis provides crucial functions in cellular regulation. The
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Yes, you can access Proteasomes: The World of Regulatory Proteolysis by Wolfgang Hilt,Dieter H. Wolf in PDF and/or ePUB format, as well as other popular books in Ciencias biológicas & Biología. We have over one million books available in our catalogue for you to explore.
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Table of contents
- Cover
- Title Page
- Copyright Page
- Contents
- 1. Proteasomes: A Historical Retrospective
- 2. Proteasomes in Prokaryotes
- 3. Proteasome Crystal Structures
- 4. Subunit Arrangement in the Human Proteasome
- 5. Active Sites and Assembly of the 20S Proteasome
- 6. The Regulatory Particle of the Yeast Proteasome
- 7. The Mammalian Regulatory Complex of the 26 S Proteasome
- 8. The 20S Proteasome Activator PA28 or 1IS Regulator
- 9. Proteasome Activators and Synthetic Modulators
- 10. The Proteasome Inhibitors and Their Uses
- 11. Intracellular Localization of Proteasomes
- 12. Primary Destruction Signals
- 13. The Ubiquitin System in Yeast
- 14. The Ubiquitin-Proteasome Pathway in Mammals: Mechanisms of Action and Involvement in Pathogenesis of Human Diseases
- 15. Deubiquitinating Enzymes and the Regulation of Proteolysis
- 16. Degradation of Ornithine Decarboxylase, a Ubiquitin-independent Proteasomal Process
- 17. The Ubiquitin-Proteasome System in Cell Cycle Control
- 18. p53 and the Proteasome Pathway
- 19. The Role of the Proteasome in Apoptosis
- 20. Function of the Proteasome in the Protein Quality Control Process of the Endoplasmic Reticulum
- 21. MHC Class I Antigen Presentation and the Proteasome Pathway
- 22. Ubiquitin, Proteasomes and Neurodegenerative Disease
- 23. The Proteasome in Posttranscriptional Control: A Protease with Endonuclease Activity
- Index