- 380 pages
- English
- PDF
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The Centrosome
About This Book
The Centrosome collates in one source the work of scientists actively engaged in studying various aspects of the centrosome, using a wide assortment of experimental approaches, techniques, and model systems. It provides useful background information on the present state of knowledge about the centrosome to researchers and advanced students interested in the organization and behavior of cells. After presenting an overview of a particular area, the articles summarize work from the authors' own laboratories and include new, unpublished material. Emphasis is on the more dynamic aspects of the subject rather than on detailed descriptions. The contributions range from descriptions of the organization of the centrosome at the molecular level to speculations on how the centrosome may affect the behavior of entire cells. Experimental studies are complemented by theoretical considerations to provide added insight into the structure and function of this organelle and by speculations on directions which appear most profitable for future studies. Controversial ideas and conflicting hypotheses, which often provide the driving force for new advances, have also been included.
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Table of contents
- Front Cover
- The Centrosome
- Copyright Page
- Table of Contents
- Contributors
- Preface
- Chapter 1. Structure and Functions of Isolated Centrosomes
- Chapter 2. Ultrastructure of Centrosome Domains and Identification of Their Protein Components
- Chapter 3. Function and Formation of Centrioles and Basal Bodies
- Chapter 4. Microtubule and Intermediate Filament Patterns around the Centrosome in Interphase Cells
- Chapter 5. Monoclonal Antibodies to Microtubule-Organizing Center Antigens
- Chapter 6. Role of Centrin in Spindle Pole Dynamics
- Chapter 7. Spindle Pole Body of Saccharomyces cerevisiae: A Model for Genetic Analysis of the Centrosome Cycle
- Chapter 8. The Centrosome in Cell Division and Development of Drosophila
- Chapter 9. Control of Centrosome Inheritance in Echinoderm Development
- Chapter 10. The Lymphocyte Centrosome
- Chapter 11. The Centrosome in Stationary and Migrating Endothelial Cells
- Chapter 12. The Centrosome: Contributions to Cell Form
- Chapter 13. Cell Polarity and Centrosomes
- Index