Percutaneous Absorption
eBook - ePub

Percutaneous Absorption

Drugs, Cosmetics, Mechanisms, Methods

  1. 1,012 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Percutaneous Absorption

Drugs, Cosmetics, Mechanisms, Methods

About this book

Updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, Fifth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, skin contamination, exposure to protein allergens, in vitro absorption methodology and the percutaneous absorption of chemical mixtures. Complete with studies on the role of the skin as a key portal of entry for chemicals into the body, this book serves as a detailed reference source for recent advances in the field, as well as an experimental guide for laboratory personnel.

Key Features:

  • Details in vivo and in vitro methods for measuring absorption, dermal decontamination, mechanisms of transdermal delivery, and the relationship of transepidermal water loss to percutaneous absorption
  • Considers a range of mathematical models, the safety evaluation of cosmetic ingredients, the absorption of hair dyes, nanoparticles for drug delivery, and other novel methods of drug delivery
  • Discusses topics including skin metabolism, the skin reservoir, and the effects of desquamation on absorption

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Information

Publisher
CRC Press
Year
2021
Print ISBN
9781138351233
eBook ISBN
9780429514999
Subtopic
Dermatology

Table of contents

  1. Cover
  2. Half Title
  3. Series Page
  4. Title Page
  5. Copyright Page
  6. Contents
  7. Editors
  8. Contributors
  9. Chapter 1 Molecular Structure and Function of the Skin Barrier
  10. Chapter 2 Mathematical Models in Percutaneous Absorption
  11. Chapter 3 In Vivo Percutaneous Absorption: A Key Role for Stratum Corneum/Vehicle Partitioning
  12. Chapter 4 The Skin Reservoir for Topically Applied Solutes
  13. Chapter 5 Chemical Partitioning into Powdered Human Stratum Corneum: A Useful In Vitro Model for Studying the Interaction of Chemicals and Human Skin
  14. Chapter 6 Variations of Hair Follicle Size and Distribution in Different Body Sites
  15. Chapter 7 In Vivo Relationship between Percutaneous Absorption and Transepidermal Water Loss
  16. Chapter 8 The Correlation between Transepidermal Water Loss and Percutaneous Absorption: An Updated Overview
  17. Chapter 9 Human Percutaneous Absorption and Transepidermal Water Loss (TEWL) Correlation
  18. Chapter 10 Evaluation of Stratum Corneum Heterogeneity
  19. Chapter 11 Regional Variation in Percutaneous Absorption: Principles and Applications to Human Risk Assessment
  20. Chapter 12 Effects of Anatomical Location on In Vivo Percutaneous Penetration in Man
  21. Chapter 13 Interrelationships in the Dose Response of Percutaneous Absorption
  22. Chapter 14 Effects of Occlusion: Percutaneous Absorption
  23. Chapter 15 Occlusion Does Not Uniformly Enhance Penetration In Vivo
  24. Chapter 16 Effect of Single versus Multiple Dosing in Percutaneous Absorption
  25. Chapter 17 Influence of Formulation on Topical and Transdermal Drug Delivery
  26. Chapter 18 In Vitro Release from Semisolid Dosage Forms: What Is Its Value?
  27. Chapter 19 Understanding Skin Metabolism–Effect on Altering In Vitro Skin: Absorption and Bioavailability of Topically Applied Chemicals
  28. Chapter 20 Phenomenon of Lateral Spread in Percutaneous Penetration
  29. Chapter 21 Clinically Pertinent Factors/Observations Affecting Percutaneous Absorption in Humans
  30. Chapter 22 Percutaneous Absorption of Chemical Mixtures
  31. Chapter 23 Dermal Decontamination and Percutaneous Absorption
  32. Chapter 24 Skin Decontamination 2020 Update
  33. Chapter 25 Chemical Warfare Agent VX Penetration through Military Uniform and Human Skin: Risk Assessment and Decontamination
  34. Chapter 26 Percutaneous Absorption of Hazardous Chemicals from Fabric into and through Human Skin
  35. Chapter 27 Percutaneous Absorption of Chemicals from Fabric (Textile)
  36. Chapter 28 The Fate of Material Remaining in Skin in In Vitro Absorption Studies
  37. Chapter 29 Skin Absorption of Hair Dyes
  38. Chapter 30 Hair Dye Penetration in Monkeys and Human Beings
  39. Chapter 31 Percutaneous Absorption of Sunscreens
  40. Chapter 32 Sunscreen Percutaneous Penetration In Vivo in Man
  41. Chapter 33 Cutaneous Metabolism of Xenobiotics
  42. Chapter 34 Chemical Modification: An Important and Feasible Method for Improving Peptide and Protein Dermal and Transdermal Delivery
  43. Chapter 35 Percutaneous Penetration of Oligonucleotide Drugs
  44. Chapter 36 Use of Microemulsions for Topical Drug Delivery
  45. Chapter 37 Transdermal Delivery of Vesicular Nanocarriers under Electrical Potential
  46. Chapter 38 Lipid-Based Vesicles (Liposomes) and Their Combination with Physical Methods for Dermal and Transdermal Drug Delivery
  47. Chapter 39 Assessment of Microneedles for Transdermal Drug Delivery
  48. Chapter 40 Clinical Testing of Microneedles for Transdermal Drug Delivery
  49. Chapter 41 Delivery of Drugs, Vaccines, and Cosmeceuticals to Skin Using Microneedle Patches
  50. Chapter 42 Microneedle Dermatotoxicology
  51. Chapter 43 Transdermal Transport by Sonophoresis
  52. Chapter 44 Effect of Tape Stripping on Percutaneous Penetration and Topical Vaccination
  53. Chapter 45 Transcutaneous Delivery of Drugs by Electroporation
  54. Chapter 46 Iontophoresis in Penetration Enhancement
  55. Chapter 47 Vehicles and Topical Therapy
  56. Chapter 48 The Role of In Vitro Skin Models in Optimization of Dermal Drug Delivery
  57. Chapter 49 Effects of Phospholipids on Skin: Use of Primary Human Keratinocytes and Fibroblasts as 2D Cell Culture Models
  58. Chapter 50 Human Cadaver Skin Viability for In Vitro Percutaneous Absorption: Storage and Detrimental Effects of Heat Separation and Freezing
  59. Chapter 51 Determination of Percutaneous Absorption by In Vitro Techniques
  60. Chapter 52 Stripping Method for Measuring Percutaneous Absorption In Vivo
  61. Chapter 53 Tape Stripping: Technique and Applications
  62. Chapter 54 Blood Flow as a Technology in Percutaneous Absorption: The Assessment of the Cutaneous Microcirculation by Laser Doppler and Photoplethysmographic Techniques
  63. Chapter 55 Confocal Raman Microspectroscopy in the Assessment of Skin Barrier Function and Drug Penetration
  64. Chapter 56 Microscopy Methods for Assessing Percutaneous Drug Penetration: Percutaneous Absorption-Drugs-Cosmetics-Mechanism-Methodology
  65. Chapter 57 Dermal Sampling Techniques with a Focus on Dermal Open Flow Microperfusion
  66. Chapter 58 Dermal-Epidermal Separation Methods: Research Implications
  67. Chapter 59 Use of Skin Absorption Data in the Safety Evaluation of Cosmetic Ingredients
  68. Chapter 60 Bioequivalence, Pharmaceutical Equivalence, and Biowaivers: Topical Dosage Forms for Local Action
  69. Chapter 61 In Vitro Human Nail Model to Evaluate Ungual Absorption and Transungual Delivery
  70. Chapter 62 Drug Permeation through Burn Eschar: Possibilities and Improvements
  71. Chapter 63 Percutaneous Penetration in Humans: Transfer of Chemicals via Skin-to-Skin Contact
  72. Chapter 64 Nanoparticles and Their Combination with Physical Methods for Dermal and Transdermal Drug Delivery
  73. Index

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Yes, you can access Percutaneous Absorption by Nina Dragićević, Howard Maibach, Howard Maibach,Nina Dragićević in PDF and/or ePUB format, as well as other popular books in Medicine & Dermatology. We have over one million books available in our catalogue for you to explore.