The Orexin System. Basic Science and Role in Sleep Pathology
eBook - PDF

The Orexin System. Basic Science and Role in Sleep Pathology

  1. 154 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

The Orexin System. Basic Science and Role in Sleep Pathology

Book details
Table of contents
Citations

About This Book

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer's disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

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Yes, you can access The Orexin System. Basic Science and Role in Sleep Pathology by M.A. Steiner, M. Yanagisawa, M. Clozel in PDF and/or ePUB format, as well as other popular books in Medicina & Neurología. We have over one million books available in our catalogue for you to explore.

Information

Publisher
S. Karger
Year
2021
ISBN
9783318068443
Topic
Medicina
Subtopic
Neurología

Table of contents

  1. Cover
  2. Frontiers of Neurology andNeuroscience
  3. The Orexin System.Basic Science and Rolein Sleep Pathology
  4. Contents
  5. Preface
  6. Twenty-Three Years of Hypocretins: The “Rosetta Stone” of Sleep/Arousal Circuits
  7. Interaction between Orexin Neurons and Monoaminergic Systems
  8. Hypocretin/Orexin Receptor Pharmacology and Sleep Phases
  9. Sleep, Orexin and Cognition
  10. Subsecond Ensemble Dynamics of Orexin Neurons Link Sensation and Action
  11. Heterogeneity of Hypocretin/Orexin Neurons
  12. Sleep and Metabolism: Implication of Lateral Hypothalamic Neurons
  13. Cellular Signaling Mechanisms of Hypocretin/Orexin
  14. Sleep Problems in Narcolepsy and the Role of Hypocretin/Orexin Deficiency
  15. The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System
  16. Causes and Consequences of Chronic Sleep Deficiency and the Role of Orexin
  17. Hypocretin/Orexin, Sleep and Alzheimer’s Disease
  18. Author Index
  19. Subject Index
  20. Cover