Animal Models and Human Reproduction
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Animal Models and Human Reproduction
About This Book
Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems.
Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART).
This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.
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Table of contents
- Animal Models and Human Reproduction
- Contents
- List of Contributors
- 1: Anatomy of the Reproductive System
- 2: Anatomy of Mammalian (Endocrine) Glands Controlling the Reproduction
- 3: Models for Investigating Placental Biology
- 4: Early Developmental Programming of the Ovarian Reserve, Ovarian Function, and Fertility
- 5: Small Non-Coding RNAS in Gametogenesis
- 6: The Ovarian Follicle of Cows as a Model for Human
- 7: Production of Energy and Determination of Competence: Past Knowledge, Present Research, and Future Opportunities in Oocyte and Embryo Metabolism
- 8: Signal Transduction Pathways in Oocyte Maturation
- 9: Pig Models of Reproduction
- 10: The Mare as an Animal Model for Reproductive Aging in the Woman
- 11: Spotlight on Reproduction in Domestic Dogs as a Model for Human Reproduction
- 12: Animal Models of Inflammation During Pregnancy
- 13: Practical Approaches, Achievements, and Perspectives in the Study on Signal Transduction in Oocyte Maturation and Fertilization: Focusing on the African Clawed Frog Xenopus laevis as an Animal Model
- 14: Prezygotic Chromosomal Examination of Mouse Spermatozoa
- 15: Molecular and Cellular Aspects of Mammalian Sperm Acrosomal Exocytosis
- 16: Sperm Chromatin Dynamics Associated with Male Fertility in Mammals
- 17: Epigenome Modification and Ubiquitin-Dependent Proteolysis During Pronuclear Development of the Mammalian Zygote: Animal Models to Study Pronuclear Development
- 18: Alterations of the Epigenome Induced by the Environment in Reproduction
- 19: Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development
- 20: Applications of Metabolomics in Reproductive Biology
- 21: Cryopreservation of Mammalian Oocytes
- Index
- Supplemental Images
- End User License Agreement