Allergic Contact Dermatitis
eBook - ePub

Allergic Contact Dermatitis

Chemical and Metabolic Mechanisms

Camilla Smith

  1. 336 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Allergic Contact Dermatitis

Chemical and Metabolic Mechanisms

Camilla Smith

Book details
Table of contents
Citations

About This Book

llergic Contact Dermatitis assesses the potential effects of xenobiotic metabolism and protein reactivity on toxicity. It reviews current knowledge of percutaneous absorption and skin metabolism and includes discussion of the xenobiotics themselves. It answers questions such as: How does sensitisation relate to protein reactivity and levels of metabolism? How we can identify potential hazards in food, cosmetics and pharmaceuticals etc?

In a world where people are becoming increasingly aware of their allergies, this up to date one-stop reference will prove an invaluable addition to the shelves of any researcher in academia, government, regulatory bodies, public health officials and, of course, the food, cosmetics and pharmaceuticals industries will find the book to be of particular relevance.

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Information

Publisher
CRC Press
Year
2023
ISBN
9781000893779
Edition
1
Topic
Medicine
Subtopic
Medical Theory, Practice & Reference

Table of contents

  1. Cover
  2. Halftitle Page
  3. Acknowledgement
  4. Title Page
  5. Copyright Page
  6. Table of Contents
  7. List of figures
  8. List of schemes
  9. List of tables
  10. Acknowledgements
  11. Preface
  12. Chapter 1 Allergic Contact Dermatitis to Small Molecule Xenobiotics
  13. Chapter 2 Skin Absorption of Chemical Allergens
  14. Chapter 3 Enzymes and Mechanisms of Xenobiotic Metabolism
  15. Chapter 4 Enzymes and Pathways of Xenobiotic Metabolism in Skin
  16. Chapter 5 Xenobiotics as Skin Sensitisers: Metabolic Activation and Detoxication, and Protein-binding Mechanisms
  17. Chapter 6 Protein-hapten Binding and Immunorecognition Events During the Sensitisation and Elicitation Stages of ACD
  18. Chapter 7 Conclusion: The Future of In Vitro Models and De Novo Prediction of Xenobiotic Skin Sensitisation, and an MHC-Peptide-Hapten Hypothesis
  19. Appendix I In vivo sensitisation data and physico-chemical properties of xenobiotics (discussed in Chapter 5)
  20. Appendix II Useful web addresses
  21. Appendix III Models and approaches for studying cutaneous metabolism
  22. References
  23. Index