The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches.

Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations
Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics
Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

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Yes, you can access Neurobiology of Bipolar Disorder by Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta,Joao L. de Quevedo in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Neuroscience. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Academic Press

Year

2020

ISBN

9780128191835

Topic

Biological Sciences

Subtopic

Neuroscience

Index

Biological Sciences

Cover image
Title page
Table of Contents
Copyright
Contributors
Foreword
Chapter 1: Tackling the heterogeneity of bipolar disorder in the era of the Research Domain Criteria (RDoC)
Chapter 2: The neurodevelopmental basis of bipolar disorder: Mechanisms and implications
Chapter 3: The neuroprogressive nature of bipolar disorder: Mechanisms and implications
Chapter 4: Immune mechanisms in bipolar disorder: Evidence and implications
Chapter 5: Mitochondrial pathways in bipolar disorder: Mechanisms and implications
Chapter 6: Neurooxidative and neuronitrosative mechanisms in bipolar disorder: Evidence and implications
Chapter 7: Mechanisms underpinning neurocognitive dysfunction in bipolar disorder
Chapter 8: The biological basis of predominant polarity
Chapter 9: The evolution of animal models for bipolar disorder
Chapter 10: Alteration in circadian rhythms in bipolar disorder: Mechanisms and implications
Chapter 11: Genetic factors in the etiology of bipolar disorder
Chapter 12: Pharmacogenomics of bipolar disorder
Chapter 13: Blood-brain barrier’s interplay with peripheral and central inflammation as a pathophysiological mechanism of bipolar disorders
Chapter 14: Induced pluripotent stem cells as tools to investigate the neurobiology of bipolar disorder and advance novel therapeutic discovery
Chapter 15: Bipolar disorder as a gliopathy
Chapter 16: Molecular imaging findings in bipolar disorder
Chapter 17: Structural neuroimaging findings in bipolar disorders
Chapter 18: Epigenetic mechanisms of bipolar disorder
Chapter 19: Bipolar disorder and cardiovascular dysfunction: Mechanisms and implications
Chapter 20: At-risk mental states for bipolar disorder
Chapter 21: Allostatic load: Implications for the pathophysiology, evolution, and treatment of bipolar disorder
Chapter 22: Bipolar disorders, obesity, and metabolic disturbances: Mechanisms and implications
Chapter 23: The microbiota-gut-brain axis and bipolar disorder
Chapter 24: The hypothalamic-pituitary-adrenal axis in bipolar disorder
Chapter 25: From intracellular signaling pathways to neural circuit dysfunction in bipolar disorder
Chapter 26: The impact of early-life stress in the development and course of bipolar disorder: Mechanisms and implications
Chapter 27: Bipolar disorder and accelerated aging: Shared mechanisms and implications
Chapter 28: Suicidal behaviors in bipolar disorder
Chapter 29: Older-age bipolar disorder
Chapter 30: Biomarkers for bipolar disorder
Chapter 31: The mechanisms of action of lithium in bipolar disorder
Chapter 32: Is there a biosignature for lithium response in bipolar disorder? Evidence and implications
Chapter 33: Physical activity and exercise in the pathophysiology and treatment of bipolar disorder
Chapter 34: Noninvasive neuromodulatory approaches for bipolar disorder
Chapter 35: Novel therapeutic drug targets for bipolar disorder
Chapter 36: The treatment of bipolar disorder in the era of precision psychiatry: Challenges and opportunities
Chapter 37: Intracortical myelination
Chapter 38: The impact of psychotropic drugs on brain functionality and connectivity in bipolar disorder
Index