Recent Developments in the Synthesis and Applications of Pyridines

Parvesh Singh

• Publisher: Elsevier
• Year: 2022
• ISBN:
  9780323914598
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.

The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.

• Includes a detailed review of recent research on the reactivity, synthesis and applications of pyridines
• Features concise accounts of the reactivity, synthetic and optimized protocols
• Discusses the medicinal, inorganic and polymer chemistry applications of pyridines

Table of contents

• Cover Image
• Title Page
• Copyright
• Table of Contents
• Contributors
• Preface
• Chapter 1 Role of pyridine and its privileged derivatives as anti-infective agents
• Chapter 2 Pyridine-based polymers and derivatives: Synthesis and applications
• Chapter 3 Synthetic strategies of functionalized pyridines and their therapeutic potential as multifunctional anti-Alzheimer's agents
• Chapter 4 Design, synthesis, and in vitro anticancer activity of thiophene substituted pyridine derivatives
• Chapter 5 The role of pyridine derivatives on the treatment of some complex diseases: A review
• Chapter 6 Pyridines in Alzheimer's disease therapy: Recent trends and advancements
• Chapter 7 Pyridine derivatives as anti-Alzheimer agents
• Chapter 8 Role of pyridines as enzyme inhibitors in medicinal chemistry
• Chapter 9 Contemporary development in the synthesis and biological applications of pyridine-based heterocyclic motifs
• Chapter 10 Synthesis of pyridine derivatives using multicomponent reactions
• Chapter 11 Recent green synthesis of pyridines and their fused systems catalyzed by nanocatalysts
• Chapter 12 Pyridine ring as an important scaffold in anticancer drugs
• Chapter 13 Recent developments in the synthesis of pyridine analogues as a potent anti-Alzheimer's therapeutic leads
• Chapter 14 Pyridine-based probes and chemosensors
• Chapter 15 Recent advances in catalytic synthesis of pyridine derivatives
• Chapter 16 Pyridine as a potent antimicrobial agent and its recent discoveries
• Chapter 17 Synthesis of pyridine derivatives for diverse biological activity profiles: A review
• Index