Nanocarriers for Drug-Targeting Brain Tumors

Lalit Kumar, Yashwant Pathak

• Publisher: Elsevier
• Year: 2022
• Print ISBN:
  9780323907736
• eBook ISBN:
  9780323914710
• Topic: Tecnologia e ingegneria
• Subtopic: Scienza dei materiali

Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and  their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors

Table of contents

• Cover
• Front Matter
• Table of Contents
• Copyright
• Dedication
• Contributors
• Preface
• List of Illustrations
• List of Tables
• 1 : An overview of the anatomy and physiology of the brain
• 2 : Blood-brain barrier and central nervous system drug delivery: Challenges and opportunities
• 3 : Challenges in targeting to brain and brain tumors
• 4 : Potential targeting sites in brain and brain tumors
• 5 : Drug resistance problems in chemotherapy
• 6 : An overview on nanocarriers
• 7 : Biomedical applications of nanocarriers in brain tumor targeting
• 8 : Solid lipid nanoparticles based drug delivery for targeting brain tumors
• 9 : Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors
• 10 : Liposomes in drug targeting to brain tumors
• 11 : Niosomes based drug delivery in targeting brain tumors
• 12 : Nanoemulsions as effective carriers for targeting brain tumors
• 13 : Mechanism of polymeric micelles for drug targeting to brain tumors
• 14 : Dendrimers as carriers for active targeting of brain tumors
• 15 : Multifunctional polymeric nanocarriers for targeting brain tumors
• 16 : Polymersomes for targeting to brain tumors
• 17 : Development and applications of gold nanoparticles for targeting brain tumors
• 18 : Gold nanoparticles in cancer theranostics
• 19 : Silver nanoparticles in brain tumor targeting
• 20 : Hybrid nanoparticles to cross the blood–brain barrier
• 21 : Targeting of lipid/polymeric (hybrid) nanoparticles to brain tumors
• 22 : Nano-enabled systems for neural tissue regenerative applications
• 23 : Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors
• 24 : Drug-loaded nanoclusters for brain targeting
• 25 : Nanomedicines for tropical diseases affecting the central nervous system
• 26 : Brain specific delivery of phytoconstituents through nanodrug wagons approach
• 27 : Multifunctional nanocarrier systems targeting brain tumors: A review
• 28 : Expert opinion on current challenges and future directions of nanocarriers for brain targeted drug delivery
• 29 : Biological nanodrugs for brain targeting
• Index
• A