Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion.

Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain.

The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided.

This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings.

Key Features:

Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases
Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications
Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment

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Yes, you can access Image-guided Focused Ultrasound Therapy by Feng Wu, Gail ter Haar, Ian Rivens, Feng Wu,Gail ter Haar,Ian Rivens in PDF and/or ePUB format, as well as other popular books in Medicine & Biotechnology in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher

CRC Press

Year

2024

ISBN

9780429530760

Edition

Topic

Medicine

Subtopic

Biotechnology in Medicine

Cover
Half Title
Series
Title
Copyright
Contents
About the Series
The International Organization for Medical Physics
About the Editors
List of Contributors
Foreword
1 Image-Guided Focused Ultrasound Therapy: Past, Current and Future
2 Physical Principles of Focused Ultrasound Therapy
3 Mechanisms for Induction of Bio-effects of Focused Ultrasound in Tissue
4 Imaged-Guided Focused Ultrasound Therapy: Physics and Clinical Applications
5 Calibration and Quality Assurance for High Intensity Focused Ultrasound Fields
6 Numerical Modelling for Simulation and Planning of Focused Ultrasound Treatments
7 Ultrasound Monitoring Techniques for Focused Ultrasound Therapy
8 Extracorporeal Ultrasound-Guided HIFU Devices – Clinical Application, Treatment Planning and B-mode Ultrasound for Real-Time Monitoring and Control of Treatment
9 Imaging Assessment of Tumour Response and Treatment Outcome after High Intensity Focused Ultrasound Ablation
10 Focused Ultrasound Treatment of the Prostate: Devices and Clinical Results
11 Ultrasound-Guided Focused Ultrasound Ablation for Uterine Fibroids
12 Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Liver Tumours
13 Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Kidney Tumours
14 Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Pancreatic Cancer
15 Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Breast Tumours
16 Clinical Application of Ultrasound-Guided High-Intensity Focused Ultrasound Treatment for Primary Bone Malignancies and Soft Tissue Sarcomas
17 Clinical Extracorporeal MR-Guided Focused Ultrasound Systems: Treatment Planning, Therapy Delivery, and Online Monitoring via Thermometry and Thermal Dose Mapping
18 Clinical Application of MR-Guided Focused Ultrasound Ablation for Uterine Fibroids
19 Clinical Application of MR-Guided Focused Ultrasound Ablation for Tumours in the Breast
20 Clinical Application of MR-Guided Focused Ultrasound Ablation for Bone Metastasis
21 Clinical Application of MR-Guided Focused Ultrasound Therapy in the Brain
22 Sonoporation: Concept, Mechanisms and Application to Cancer Treatment
23 Nano/Microbubble-Assisted Ultrasound for Drug Delivery in Cancer
24 Anaesthesia, Ventilation and Immobilisation Strategies for Focused Ultrasound Therapy (with Special Reference to High-Frequency Ventilation)
25 Triggered Temperature-Sensitive Liposome Release by Focused Ultrasound for Localised Drug Delivery
26 Transcranial Ultrasound–Mediated Blood-Brain Barrier Disruption for Targeted Drug Delivery
27 Histotripsy: Focused Ultrasound Therapy by Mechanical Tissue Fractionation
28 Focused Ultrasound Ablation Enhancement of Specific Antitumour Immunity
29 Focused Ultrasound Therapy for Treatment of Pain
Index