Transglutaminase

Fundamentals and Applications

Yi Zhang,Benjamin K. Simpson

• Publisher: Academic Press
• Year: 2024
• ISBN:
  9780443191695
• Topic: Biological Sciences
• Subtopic: Biophysics
• Index: Biological Sciences

Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases.

• Brings together basic knowledge and applied research on transglutaminase biology
• Considers a range of application areas, from biomedicine to drug development, tissue engineering, food processing, and materials synthesis
• Includes instructive protocols for basic and applied transglutaminase research
• Features chapter contributions from global leading experts in the field, across disciplines and applications

Table of contents

• Cover image
• Title page
• Table of Contents
• Foundations and frontiers in enzymology series
• Copyright
• An introduction to transglutaminases
• 1. Transglutaminases from microorganisms
• 2. Transglutaminases from plant sources
• 3. Transglutaminases from animals
• 4. Newly engineered transglutaminases
• 5. Transglutaminase 2 in neurological conditions
• 6. Transglutaminases in cardiovascular health and disease
• 7. Microbial transglutaminase in drug development
• 8. Transglutaminases in meat and seafood bioprocessing
• 9. Transglutaminase in dairy processing
• 10. Transglutaminase in noodles, pastas, and baked products
• 11. Transglutaminase in textile, wool, silk, and leather processing
• 12. Immobilization of transglutaminases and transglutaminase as immobilization agent
• 13. Industrial production of transglutaminase
• Index