Microbial Biofilms

Role in Human Infectious Diseases

Mukesh Kumar Yadav, Jae Jun Song, Jorge E. Vidal, Mukesh Kumar Yadav,Jae Jun Song,Jorge E. Vidal

• Publisher: Academic Press
• Year: 2024
• ISBN:
  9780443192531
• Topic: Biological Sciences
• Subtopic: Microbiology
• Index: Biological Sciences

Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.

• Fulfills the knowledge gap in biofilm study
• Focuses on new and emerging concepts in microbial biofilm research
• Highlights the various anti-biofilm strategies
• Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases

Table of contents

• Cover image
• Title page
• Table of Contents
• Copyright
• List of contributors
• 1. Application of nanoparticles to combat dental biofilms
• 2. Streptococcus biofilms: role in human infectious diseases
• 3. Single-species and multispecies biofilms causing infections
• 4. Gut microbiota: role of biofilms in human health
• 5. Natural compounds to combat microbial biofilms
• 6. Vaginal microbiota biofilm in pregnancy and birth outcome: function and prospects
• 7. Microbial biofilms and their role in acute and chronic pathogenesis
• 8. Surface modification: strategies to prevent microbial growth on medical implants
• 9. Microbial biofilms and the skin microbiome
• 10. Cell-to-cell interaction and cell signaling in biofilm formation
• 11. A concise review on genes involved in biofilm-related disease and differential gene expression in medical-related biofilms
• 12. Next-generation sequencing: role in microbial biofilm study
• 13. Electrical signaling in growth dynamics of microbial biofilms
• Index