Conceptual Breakthroughs in The Evolutionary Biology of Aging
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Conceptual Breakthroughs in The Evolutionary Biology of Aging

  1. 296 pages
  2. English
  3. ePUB (mobile friendly)
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eBook - ePub

Conceptual Breakthroughs in The Evolutionary Biology of Aging

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About This Book

Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field's breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures.

  • Reviews cell-molecular theories of aging in the light of evolutionary biology
  • Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors
  • Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology

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Yes, you can access Conceptual Breakthroughs in The Evolutionary Biology of Aging by Kenneth R. Arnold,Michael R. Rose, John C. Avise in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2023
ISBN
9780128215463
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. Foreword from the Series Editor, John C. Avise
  7. Chapter One. Introduction
  8. Chapter Two. 384–322B.C: The first biologist on aging
  9. Chapter Three. 1645: A tale of two Bacons
  10. Chapter Four. 1881: Natural selection is the ultimate determinant of aging
  11. Chapter Five. 1922: Early laboratory experiments on demography
  12. Chapter Six. 1928: Basic mathematics of selection with age-structure
  13. Chapter Seven. 1930: First explanation of aging by age-specific patterns of selection
  14. Chapter Eight. 1941: First proposal of the general idea of declining force of natural selection
  15. Chapter Nine. 1946–57: Verbal hypotheses for the evolutionary genetics of aging
  16. Chapter Ten. 1953: Absence of a Lansing effect in inbred Drosophila
  17. Chapter Eleven. 1961: Presence of aging in a fish with continued adult growth
  18. Chapter Twelve. 1966: Mathematical derivation of the forces of natural selection
  19. Chapter Thirteen. 1960s: Falsification of the somatic mutation theory
  20. Chapter Fourteen. 1960s: Falsification of the translation error catastrophe theory
  21. Chapter Fifteen. 1968: Proposal of experimental designs to test evolutionary theories of aging
  22. Chapter Sixteen. 1968: Accidental evolutionary postponement of aging
  23. Chapter Seventeen. 1970: Experimental evolution of accelerated aging in Tribolium
  24. Chapter Eighteen. 1970–74: Development of evolutionary genetics of age-structured populations
  25. Chapter Nineteen. 1975: Application of Charlesworth's theory to the evolution of aging
  26. Chapter Twenty. 1980: Full development of evolutionary genetic theory for aging
  27. Chapter Twenty One. 1980–81: Quantitative genetic tests of hypotheses for the evolution of aging
  28. Chapter Twenty Two. 1980–84: Mitigation of aging by postponing the decline in forces of natural selection
  29. Chapter Twenty Three. 1977–1988: Characterization of Caenorhabditis elegans mutants with extended lifespan
  30. Chapter Twenty four. 1982–85: Further mathematical characterization of evolution with antagonistic pleiotropy
  31. Chapter Twenty Five. 1984: Genetic covariation is shifted to positive values by inbreeding
  32. Chapter Twenty Six. 1984: Direct demonstration of nonaging in fissile species
  33. Chapter Twenty seven. 1989: Additional experiments support antagonistic pleiotropy
  34. Chapter Twenty eight. 1985: Genotype-by-environment interaction shown for aging
  35. Chapter Twenty nine. 1985–onward: Evolutionary physiology of aging
  36. Chapter Thirty. 1987: Accelerated senescence explained in terms of mutation accumulation with inbreeding depression
  37. Chapter Thirty one. 1988: Reverse evolution of aging
  38. Chapter Thirty two. 1985–88: Genetic analysis of aging in males
  39. Chapter Thirty three. 1987–1991: Quantitative genetic analysis of how many genes determine aging
  40. Chapter Thirty four. 1988: Evidence for senescence in the wild
  41. Chapter Thirty five. 1989–onward: Molecular genetic variation at selected loci in the evolution of aging
  42. Chapter Thirty six. 1988–89: The evolutionary logic of extending lifespan by dietary restriction
  43. Chapter Thirty seven. 1992: Selection for stress resistance increases lifespan
  44. Chapter Thirty eight. 1992: In late adult life, mortality rates stop increasing
  45. Chapter Thirty nine. 1993–1995: Evolution of increased longevity among mammals, in the wild and the lab
  46. Chapter Forty. 1993: Evolutionary physiology of dietary restriction
  47. Chapter Forty one. 1993: Genetic association between dauer metabolic arrest and increased lifespan
  48. Chapter Forty two. 1992–95: Experimental evolution of aging is connected to development
  49. Chapter Forty three. 1994–96: Evidence for mutation accumulation affecting virility and aging
  50. Chapter Forty four. 1996–98: Physiological research on evolution of aging supports organismal mechanisms
  51. Chapter Forty five. 1996: Late-life mortality plateaus explained using evolutionary theory
  52. Chapter Forty six. 1998–2003: Falsification of lifelong heterogeneity models for the cessation of aging
  53. Chapter Forty seven. 1998–2000: Discovery of Drosophila mutants that sometimes increase longevity
  54. Chapter Forty eight. 1999–2004: Nematode longevity mutants show antagonistic pleiotropy
  55. Chapter Forty nine. 2002–06: Evolution of life-history fits evolutionary analysis of late life
  56. Chapter Fifty. 2003–2005: Breakdown in correlations between stress resistance and aging
  57. Chapter Fifty one. 2007–11: Development of demographic models that separate aging from dying
  58. Chapter Fifty two. 2010: Studying the evolutionary origins of aging in bacteria
  59. Chapter Fifty three. 2010: Genome-wide sequencing of evolved aging reveals many sites
  60. Chapter Fifty four. 2011–19: Evolutionary transcriptomics also reveal complex physiology of aging
  61. Chapter Fifty five. 2012: Late life is physiologically different from aging
  62. Chapter Fifty six. 2014: Genomic studies of centenarians have low scientific power
  63. Chapter Fifty seven. 2015: Evolutionary genetic effects produce two evolutionary biologies of aging
  64. Chapter Fifty eight. 2016: Experimental evolution can produce nonaging young adults
  65. Chapter Fifty nine. 2017: The heart is implicated in the evolution of aging
  66. Chapter Sixty. 2020: Evolutionary adaptation to diet and its impact on healthspan
  67. Conclusion
  68. Glossary
  69. Author Index
  70. Index