Inflammation and Natural Products

Sreeraj Gopi, Augustine Amalraj, Ajaikumar B. Kunnumakkara, Sabu Thomas

• Publisher: Academic Press
• Year: 2021
• Print ISBN:
  9780128192184
• eBook ISBN:
  9780128192191
• Topic: Medicine
• Subtopic: Alternative & Complementary Medicine

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries. - Increases the knowledge of anti-inflammatory activities of natural products and their mechanism of action - Provides a new perspective and forward-thinking ideas to researchers, the scientific community and industry - Intensifies the understanding of synergistic action of biologically active naturally occurring molecules and their biological activities against inflammation

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• Contributors
• 1 Inflammation, symptoms, benefits, reaction, and biochemistry
• REMOVED: Natural products as modulators of signaling in inflammation
• 2 Natural products with antiinflammatory activities against autoimmune myocarditis
• 3 Multitarget approach for natural products in inflammation
• 4 Antiinflammatory activity of natural dietary flavonoids
• 5 Antiinflammatory effects of turmeric (Curcuma longa) and ginger (Zingiber officinale)
• 6 Antiinflammatory activity of Boswellia
• 7 Antiinflammatory activity of galangal
• 8 Antiinflammatory natural products from marine algae
• 9 Medicinal plants and their potential use in the treatment of rheumatic diseases
• 10 Natural product–derived drugs for the treatment of inflammatory bowel diseases (IBD)
• 11 Smart drug delivery systems of natural products for inflammation: From fundamentals to the clinic
• 12 Systems pharmacology and molecular docking strategies prioritize natural molecules as antiinflammatory agents
• 13 Bioavailability, pharmacokinetic, pharmacodynamic, and clinical studies of natural products on their antiinflammatory activities
• 14 Supplements and diets for antiinflammation
• 15 Values of natural products to future antiinflammatory pharmaceutical discovery
• 16 Identification of toxicology biomarker and evaluation of toxicity of natural products by metabolomic applications
• Index