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Pathogenesis, Treatment and Prevention of Leishmaniasis
Mukesh Samant,Satish Chandra Pandey
- 280 pages
- English
- ePUB (mobile friendly)
- Only available on web
Pathogenesis, Treatment and Prevention of Leishmaniasis
Mukesh Samant,Satish Chandra Pandey
About This Book
Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis.
- Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment
- Discusses novel approaches to study parasite infection and treatment
- Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
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Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Chapter 1. Leishmaniasis: an overview of evolution, classification, distribution, and historical aspects of parasite and its vector
- Chapter 2. Neoteric strategies for vector control and identification of zoonotic reservoirs
- Chapter 3. Recent advances in the diagnostic methods of Leishmaniasis
- Chapter 4. Recent advances on computational approach towards potential drug discovery against leishmaniasis
- Chapter 5. DNA microarray analysis of Leishmania parasite: strengths and limitations
- Chapter 6. Drug resistance and repurposing of existing drugs in Leishmaniasis
- Chapter 7. Novel nanotechnology-based approaches in the treatment of leishmaniasis
- Chapter 8. Natural products as a novel source for antileishmanial drug development
- Chapter 9. Evaluation of biomarkers to monitor therapeutic intervention against visceral leishmaniasis
- Chapter 10. Development of a successful vaccine for leishmaniasis: possibilities and challenges
- Chapter 11. Interferon-Îł: a key cytokine in leishmaniasis
- Chapter 12. Apoptosis in Leishmania: biochemical footprint and its relevance to surmount leishmaniasis
- Chapter 13. Immunological determinants, host immune responses, and animal models of visceral leishmaniasis
- Index