- 736 pages
- English
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Biochemistry of Lipids, Lipoproteins and Membranes
About This Book
Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences.
As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis.
- Fully revised to cover new and emerging topics
- Provides an important bridge between broad-based biochemistry research and application
- Presents key concepts that are supported by figures and models to improve understanding
- Includes references from current literature in each chapter to facilitate in-depth study
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Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Chapter 1. Functional roles of lipids in biological membranes
- Chapter 2. Methods of lipid analysis
- Chapter 3. Fatty acid and phospholipid biosynthesis in prokaryotes
- Chapter 4. Lipid metabolism in plants
- Chapter 5. Fatty acid handling in mammalian cells
- Chapter 6. Fatty acid desaturation and elongation in mammals
- Chapter 7. Phospholipid synthesis in mammalian cells
- Chapter 8. Phospholipid catabolism
- Chapter 9. Sphingolipids
- Chapter 10. Cholesterol synthesis
- Chapter 11. Structure and function of lipid droplets
- Chapter 12. Bile acid metabolism
- Chapter 13. Lipid modification of proteins
- Chapter 14. Inter- and intra-membrane lipid transport
- Chapter 15. High-density lipoproteins: Metabolism and protective roles
- Chapter 16. Assembly and secretion of triacylglycerol-rich lipoproteins
- Chapter 17. Lipoprotein(a)
- Chapter 18. Lipoprotein receptors
- Chapter 19. Atherosclerosis
- Chapter 20. Diabetic dyslipidaemia
- Index