- 752 pages
- English
- ePUB (mobile friendly)
- Only available on web
About This Book
Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce.
- Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences
- Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics
- Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology
Frequently asked questions
Information
Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- Chapter 1. Overview of biopharmaceutics and pharmacokinetics
- Chapter 2. Pharmacokinetics and biopharmaceutics: âa leader or attendantâ
- Chapter 3. Dose, dosage regimen, and dose adjustment in organ failure
- Chapter 4. Pharmacokinetics aspects of structural modifications in drug design and therapy
- Chapter 5. Biopharmaceutical considerations in the pediatric and geriatric formulation development
- Chapter 6. Kinetics of maternalâfetal drug transfer
- Chapter 7. Chronopharmacokinetics
- Chapter 8. Pharmacokinetic characterization of drugs and new product development
- Chapter 9. Pharmacokinetics modeling in drug delivery
- Chapter 10. Drug metabolic kinetics
- Chapter 11. Pharmacogenomics and drug metabolism
- Chapter 12. Revamping the pharmacokinetics of poorly soluble drugs using different formulations
- Chapter 13. Molecular mechanisms of circadian rhythm and its influence on the pharmacokinetics of drugs
- Chapter 14. Influence of fever on pharmacokinetics of drugs
- Chapter 15. Implications for sex-related issues in clinical pharmacology and biopharmaceutics
- Chapter 16. Bioanalytical method development and validation for establishing bioavailability and bioequivalence
- Chapter 17. Factors affecting the stability of drugs and their metabolites in biological matrices
- Chapter 18. Pharmacokinetics aspects of biotechnological products
- Chapter 19. Factors affecting the pharmacokinetics of the liposomal drugs
- Chapter 20. Microdialysis: an emerging technique for pharmacokineticâpharmacodynamic profiling
- Chapter 21. Positron emission tomography as a noninvasive tool in pharmacokinetic studies
- Chapter 22. âOrgan-on-a-chipâ-based physiologically relevant pharmacokinetic models
- Chapter 23. Artificial intelligence in preventive and managed healthcare
- Chapter 24. Software used in ADME computation
- Index