Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors' environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications.

Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.

Examines the impact of biological sex and gender on gene expression through epigenetic mechanisms, and its relationship to human biology and disease
Presents the current state of our understanding of how environmental experience is translated to future generations in a sex specific manner
Features chapter contributions from international leaders in the field

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Yes, you can access Sex, Gender, and Epigenetics by Marianne Legato J,Dov Feldberg,Marek Glezerman in PDF and/or ePUB format, as well as other popular books in Medicine & Genetics in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Academic Press

Year

2023

ISBN

9780128239384

Topic

Medicine

Subtopic

Genetics in Medicine

Cover image
Title page
Table of Contents
Copyright
Dedication
Contributors
Chapter 1: Exploring how we become what we are
Chapter 2: A critical view of the revolution of precision medicine: genetics, epigenetics, sex, and gender
Chapter 3: Genetic and epigenetic contributions to female-biased lupus disease: X-chromosome inactivation in immune cells
Chapter 4: Genetic, molecular, and cellular determinations of sex-specific cardiovascular traits
Chapter 5: Epigenetics and mental and physical health of children born after ART
Chapter 6: Epigenetic aspects of male infertility treatment
Chapter 7: Evidence for assisted reproductive technology associated epigenetic variation in humans
Chapter 8: Deconvoluting the functional role of DNA methylation in trauma; Implications for epigenetic therapy and prospects of targeted “epigenetic therapy”
Chapter 9: Antenatal Origins of Health and Disease—A clinician's perspective
Chapter 10: Maternal anxiety during pregnancy and the lack of fetal DNA methylation in cord blood
Chapter 11: DNA methylation and other epigenetic modifications mediating the transgenerational impacts of paternal exposures on offspring phenotypes
Chapter 12: Epigenetics and psychiatry
Chapter 13: Integrative transcriptomics reveals sexually dimorphic control of the cholinergic/neurokine interface in schizophrenia and bipolar disorder
Chapter 14: Gender specific neurobehavioral and gene expression changes in a valproic acid (VPA)–induced mouse model of autistic like behavior and correction by S-adenosylmethionine (SAMe)
Chapter 15: Genetics and epigenetics of the one-carbon metabolism pathway in autism spectrum disorder: Role of a sex-specific brain epigenome
Chapter 16: Novel mechanisms for gene regulation: Chemical tags on RNA molecules
Chapter 17: Genes, environments, and epigenetics
Chapter 18: Epigenetic mechanisms linking poor maternal nutrition during pregnancy to the cardio-metabolic health of offspring
Chapter 19: Epigenetic aspects of human reproduction and early pregnancy
Chapter 20: Sex-specific impact of maternal metabolic environment on the development of the offspring, from gametogenesis to infancy and beyond
Chapter 21: Mitochondria as epigenetic regulators of reproductive aging
Chapter 22: The fetal programming of telomere biology hypothesis
Chapter 23: Brain organoids modeling of genetic and environmental impact on neurodevelopmental traits
Index