Conformation in Biology and Drug Design
The Peptides: Analysis, Synthesis, Biology, Vol. 7
- 516 pages
- English
- PDF
- Available on iOS & Android
Conformation in Biology and Drug Design
The Peptides: Analysis, Synthesis, Biology, Vol. 7
About This Book
The Peptides: Analysis, Synthesis, Biology, Volume 7: Conformation in Biology and Drug Design focuses on the analysis of peptides, emphasizing the use of physical methods in peptide conformational analysis and the relationship of conformational properties of peptides to biological properties. This book consists of nine chapters. Chapter 1 provides a brief overview of the perspective on the application of physical methods to peptide conformational analysis. The use of circular dichroism (CD) spectroscopy to examine the conformational properties of peptides in solution is elaborated in Chapter 2, while the use of fluorescence spectroscopy to examine the special relationships of aromatic side-chain groups to one another is discussed in Chapter 3. In Chapter 4, the use of various theoretical methods to calculate the conformations of peptides is described. The methods used to stimulate peptide conformations and dynamics are outlined in Chapter 5. The last four chapters examine various aspects of the use of nuclear magnetic resonance (NMR) in peptide conformational analysis. This volume is suitable for biologists, specialists, and researchers interested in peptides and proteins.
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Table of contents
- Front Cover
- Conformation in Biology and Drug Design
- Copyright Page
- Table of Contents
- Contributors
- Preface
- Nomenclature and Abbreviations
- Chapter 1. A Perspective on the Application of Physical Methods to Peptide Conformational-Biological Activity Studies
- Chapter 2. Circular Dichroism of Peptides
- Chapter 3. Application of Fluorescence Techniques in Studies of Peptide Conformations and Interactions
- Chapter 4. Theoretical Methods in the Analysis of Peptide Conformation
- Chapter 5. Theoretical Simulation of Conformation, Energetics, and Dynamics of Peptides
- Chapter 6. Paramagnetic Metal Ions as Nuclear Magnetic Resonance Probes of Peptide Conformation in Solution
- Chapter 7. Nuclear Magnetic Resonance Studies of PeptideâMacromolecule Interactions
- Chapter 8. Solid-State Nuclear Magnetic Resonance of Peptides
- Chapter 9. Modern Nuclear Magnetic Resonance Spectroscopy of Peptides
- Index