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Cytogenetics of Cells in Culture
About This Book
Cytogenetics of Cells in Culture is a compendium of papers that deals with techniques to detect patterns of DNA replication, cellular control mechanisms, and chromosome analyses with automated instrumentation. Some papers discuss the effects of cell hybridization and of noxious substances such as radiation, chemical agents, and viruses on chromosomal patterns. Other papers focus on the influence of altered chromosomal complement on the survival of cells to long-term tissue culture or to ionizing radiation treatment. A couple of papers points out that naturally occurring chromosomal abnormalities in mammalian populations are relatively rare and are not necessarily associated with physical defects or disease. One paper notes that chromosomes in cells with different functions have different patterns of replication in which the changes are small and hidden. The chromosomes will usually be neutralized showing little of the characteristic pattern of replication or condensation during the early cleavage stages, that will later change into differentiated characteristic ways for each tissue type. Another paper describes chromosome breakage associated with viruses and DNA inhibitors. The compendium can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or physiology.
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Table of contents
- Front Cover
- Cytogenetics of Cells in Culture
- Copyright Page
- Table of Contents
- CHARLES MARC POMERAT
- LIST OF CONTRIBUTORS
- PREFACE
- Chapter 1. CYTOGENETIC ALTERATIONS IN MIXED CULTURES OF MAMMALIAN SOMATIC CELLS IN VITRO
- Chapter 2. HYBRIDIZATION OF SOMATIC CELLS JN VITRO
- Chapter 3. SELECTION PRESSURE IN MAMMALIAN CELL POPULATIONS
- Chapter 4. PHASE CINEMATOGRAPHY STUDIES ON THE EFFECTS OF RADIATION AND OF SOME CHEMICALS ON CELLS AND CHROMOSOMES
- Chapter 5. CELLULAR INTERPRETATION OF ASPECTS OF THE ACUTE MAMMALIAN RADIATION SYNDROME
- Chapter 6. RETENTION OF EUPLOIDY AND MUTAGENICITY OF HETEROCHROMATIN IN CULTURE
- Chapter 7. THE NATURE, ORIGIN, AND GENETIC IMPLICATIONS OF STRUCTURAL ABNORMALITIES OF THE SEX CHROMOSOMES IN MAN
- Chapter 8. CHROMOSOME STUDIES IN THE GENERAL POPULATION
- Chapter 9. ALTĂRATIONS CHROMOSOMIQUES DANS DES CELLULES CULTIVĂES EN PRĂSENCE D'EXTRAITS TISSULAIRES HĂTĂROSPĂCIFIQUES1
- Chapter 10. CHROMOSOMAL STUDIES ON HUMAN LEUCOCYTES FOLLOWING TREATMENT WITH RADIOACTIVE IODINE IN VIVO AND IN VITRO
- Chapter 11. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS
- Chapter 12. REGULATION OF DNA REPLICATION AND VARIEGATION-TYPE POSITION EFFECTS
- Chapter 13. IDENTIFICATION AND CHARACTERIZATION OF HUMAN CHROMOSOMES BY DNA REPLICATION SEQUENCE
- Chapter 14. MUTAGENIC RESPONSE OF HUMAN SOMATIC CELL LINES
- Chapter 15. DNA SYNTHESIS AND CHROMOSOMAL MORPHOLOGY OF CHINESE HAMSTER CELLS CULTURED IN MEDIA CONTAINING N-DEACETYL-N-METHYLCOLCHICINE (COLCEMID)
- Chapter 16. HETEROCHROMATIN IN THE HUMAN MALE
- Chapter 17. CHROMOSOME BREAKAGE ASSOCIATED WITH VIRUSES AND DNA INHIBITORS
- Chapter 18. QUANTITATION AND AUTOMATION OF CHROMOSOMAL DATA WITH SPECIAL REFERENCE TO THE CHROMOSOMES OF THE HAMSHIRE PIG
- AUTHOR INDEX