Monoamine Oxidases and Their Selective Inhibition
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Monoamine Oxidases and Their Selective Inhibition

Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979

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eBook - PDF

Monoamine Oxidases and Their Selective Inhibition

Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979

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Table of contents
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About This Book

Monoamine Oxidases and Their Selective Inhibition, Volume IV, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. The discovery of the selective monoamine oxidase (MAO) inhibitors, such as clorgyline and deprenyl, has given a new impetus to MAO research as well as to the clinical applicability of these compounds. This volume contains 21 papers by researchers and clinicians from eight different countries. It begins with papers on the pharmacological effects and the biochemical mode of actions of deprenyl as well as some other new selective inhibitors. This is followed by communications concerning the biochemical methods applied in the study of the nature of MAO in the mitochondrial membrane. Finally, the neurologists provide an account of their experience with the clinical application of deprenyl, and other inhibitors in Parkinsonian patients. They also discuss the essential role of the dopaminergic mechanism with respect to the disease.

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Information

Publisher
Pergamon
Year
2013
ISBN
9781483147864

Table of contents

  1. Front Cover
  2. Monoamine Oxidases and Their Selective Inhibition
  3. Copyright Page
  4. Table of Contents
  5. PREFACE
  6. LIST OF CONTRIBUTORS
  7. CHAPTER 1. THE ANALYSIS OF AMINE OXIDASES BY THE USE OF ENZYMEINHIBITORS
  8. CHAPTER 2. RECENT CLINICAL STUDIES IN MONOAMINE OXIDASE INHIBITION
  9. CHAPTER 3. STRUCTURE-ACTIVITY RELATIONSHIP OF SELECTIVE INHIBITORSOF MAO-B
  10. CHAPTER 4. SELECTIVE INHIBITORS OF MAO-B WITH DIFFERENT PHARMACOLOGICALPROFILES
  11. CHAPTER 5. 13 METHAMPHETAMINE A THBRAHfiUTIDALLY IMPORTANT METABOLITE OF JSPRENiL?
  12. CHAPTER 6 . MONOAMINE OXIDASE INHIBrTOIJS (MAOIs) AND FOOD INTAKE
  13. CHAPTER 7. DEPRENYL INHIBITS DOPAMINE UPTAKE IN THE RAT STRIATUM IN VIVO
  14. CHAPTER 8. GEL CHROMATOGRAPHY OF PHENYLALKYLAMINES
  15. CHAPTER 9. Human platelet MAO-B - one single enzyme form?
  16. CHAPTER 10. SUICIDE INHIBITORS OF MONOAMINE OXIDASE1
  17. chapter 11. PURIFICATION AND PROPERTIES OP THE PHENYLHYDRAZINE ADDUCTSOP TRIMETHYLAMINE DEHYDROGENASE AND OP MONOAMINE OXIDASE
  18. CHAPTER 12. SELECTIVE INHIBITION OF MAO INDUCED BY NEW ANTIDEPRESSANTDERIVATIVES OF PYRAZINE-INDOLE
  19. CHAPTER 13. SELECTIVE INHIBITION OF MONOAMINE OXIDASE TYPE A BY SOME4-AMINOPHENYLISOPROPYLAMINE COMPOUNDS
  20. CHAPTER 14. THIOL COMPOUNDS AND MDNOAMINE OXIDASE IN RAT LIVER AND BRAIN
  21. CHAPTER 15. ENZYME STIMULATION AMD INHIBITION AS AN APPROACH TOTHERAPY FOR PARKINSON'S DISEASE
  22. CHAPTER 16. PHARMACO-THERAPY OF PARKINSONISM
  23. CHAPTER 17.LINICAL EXPERIENCE IN EXTRAPYRAMIDAL DISEASE WITH SELECTIVEMAO - BINHIBITOR , DEPRENYL
  24. CHAPTER 18. (-)DEPRENYL HAS A BAND OF SELECTIVITY FOR THERAPEUTIC ACTION
  25. CHAPTER 19. THE NNACTION OF L- DEPRENYLINL - DOPA TREATED PARKINSONI ANPATIENTS , WITHSPECIAL REFERENCE TO THE1ON- OFF1EF FECT
  26. CHAPTER 20. LONG-TERM L-DEPRENYL TREATMENT OF ON-OFF PHENOMENA IN PARKINSON'S DISEASE
  27. CHAPTER 21. LATE KINETIC EFFECTS OF L-DOPA AND COMBINED THERAPYIN PARKINSON'S DISEASE
  28. SUBJECT INDEX