Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects.

This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles).

Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance.

This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

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Yes, you can access Binding, Transport and Storage of Metal Ions in Biological Cells by Wolfgang Maret, Anthony Wedd, Wolfgang Maret, Anthony Wedd in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Inorganic Chemistry. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Royal Society of Chemistry

Year

2014

ISBN

9781782622826

Edition

Topic

Physical Sciences

Subtopic

Inorganic Chemistry

Cover
Title
Copyright
Preface
Contents
Chapter 1 Overview
Chapter 2 Sodium. Its Role in Bacterial Metabolism
Chapter 3 Potassium
Chapter 4 Magnesium
Chapter 5 Calcium
Chapter 6 Vanadium
Chapter 7 Chromium
Chapter 8 Molybdenum and Tungsten
Chapter 9 Manganese
Chapter 10 Iron in Eukarya
Chapter 11 Iron Uptake and Homeostasis in Prokaryotic Microorganisms
Chapter 12 Iron-sulfur Clusters
Chapter 13 Ferritin and Its Role in Iron Homeostasis
Chapter 14 Cobalt and Nickel
Chapter 15 Platinum
Chapter 16 Copper in Prokaryotes
Chapter 17 Copper in Mitochondria
Chapter 18 Copper in Eukaryotes
Chapter 19 Silver
Chapter 20 Gold
Chapter 21 Metallothioneins
Chapter 22 Zinc
Chapter 23 Cadmium
Chapter 24 Mercury
Chapter 25 Antimony and Bismuth
Chapter 26 Actinides in Biological Systems
Chapter 27 Aluminium
Chapter 28 Lead
Subject Index