Rifaximin: A Poorly Absorbed Antibiotic
Pharmacology and Clinical Use. Reprint of: Chemotherapy 2005, Vol. 51, Suppl. 1
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Rifaximin: A Poorly Absorbed Antibiotic
Pharmacology and Clinical Use. Reprint of: Chemotherapy 2005, Vol. 51, Suppl. 1
About This Book
Rifaximin is a semisynthetic rifamycin which is not absorbed from the gastrointestinal tract. It has been available in Europe and other countries for several years, and has recently been approved for treatment of traveler's diarrhea in the United States. Because of its broad spectrum of anti-microbial activity, rifaximin has been used with success in the treatment of infectious diarrhea, hepatic encephalopathy, small intestinal bacterial overgrowth, inflammatory bowel disease, and colonic diverticular disease. Potential indications include the irritable bowel syndrome and chronic constipation, Clostridium difficile infection and bowel preparation before colorectal surgery.In this publication both the present and future clinical use of rifaximin as well as the pharmacology behind it are extensively reviewed. Compiling the latest information on this remarkably active antibacterial agent, it will be an essential resource for infectiologists, gastroenterologists, and digestive surgeons alike.
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Table of contents
- Cover
- Contents
- Foreword
- Preface
- The Pathogenesis of Gastrointestinal Bacterial Overgrowth
- Pathophysiology and Impact of Enteric Bacterial and Protozoal Infections: New Approaches to Therapy
- Rifaximin, a Poorly Absorbed Antibiotic: Pharmacology and Clinical Potential
- Rifaximin: In vitro and in vivo Antibacterial Activity â A Review
- Rifaximin in the Treatment of Infectious Diarrhea
- Antibiotic-Associated Diarrhea and Pseudomembranous Colitis: Are They Less Common with Poorly Absorbed Antimicrobials?
- Management of Hepatic Encephalopathy: Role of Rifaximin
- Management of Inflammatory Bowel Disease: Does Rifaximin Offer Any Promise?
- Treatment of Small Intestine Bacterial Overgrowth and Related Symptoms by Rifaximin
- Management of Diverticular Disease: Is There Room for Rifaximin?
- Mechanical and Antibacterial Bowel Preparation in Colon and Rectal Surgery
- Rifaximin, a Peculiar Rifamycin Derivative: Established and Potential Clinical Use Outside the Gastrointestinal Tract
- Author Index
- Subject Index