This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.

Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.

Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: Zanichelli

--> Contents:

Foreword — Improving the Culture of Medicine
About the Authors
Precautions and Warnings Before Using This Book
To Cure, Heal or Repair
Hunting for Drugs
Laboratory Studies
First Time in Humans
Only Probabilities, Never Certainties
Approval or Rejection
Vigilance, Revisions, New Indications
Predicting the Drugs of the Future
Not Every Pill is a Proper Drug
If You Want to Know More...
Myths to be Dispelled
Did You Know That...
Index

-->
--> Readership: Undergraduate, post-graduate and researchers in basic biomedical, biological and chemical disciplines; physicians; health service policy-makers and members of the general public. -->

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Yes, you can access How Medicines Are Born: The Imperfect Science Of Drugs by Lisa Vozza, Maurizio D'incalci, Andreas Gescher in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Science General. We have over one million books available in our catalogue for you to explore.

Information

Publisher

World Scientific Publishing Europe Ltd

Year

2017

ISBN

9781786342997

Topic

Biological Sciences

Subtopic

Science General

Index

Biological Sciences

Contents
Foreword — Improving the Culture of Medicine
About the Authors
Precautions and Warnings before Using this Book
Chapter 1 To Cure, Heal or Repair
Chapter 2 Hunting for Drugs
Chapter 3 Laboratory Studies
Chapter 4 First Time in Humans
Chapter 5 Only Probabilities, Never Certainties
Chapter 6 Approval or Rejection
Chapter 7 Vigilance, Revisions, New Indications
Chapter 8 Predicting the Drugs of the Future
Chapter 9 Not Every Pill is a Proper Drug
If You Want to Know More…
Myths to be Dispelled
Did You Know That…
Index