The World Scientific Encyclopedia of Nanomedicine and Bioengineering II

Bioimplants, Regenerative Medicine, and Nano-Cancer Diagnosis and Phototherapy(A 3-Volume Set)Volume 1: Synthesis and Biomedical Applications of Graphene Quantum DotsVolume 2: Advanced Nanomaterials for Bioimaging and Cancer TherapyVolume 3: Design of Bioactive Materials for Bone Repair and...

Maoquan Chu;Wei Xia;Jiang Chang;

• Publisher: WSPC
• Year: 2017
• ISBN:
  9789814667609
• Topic: Technology & Engineering
• Subtopic: Biomedical Science
• Index: Technology & Engineering

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This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine.

An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues.

This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.

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--> Contents:

• Volume 1: Synthesis and Biomedical Applications of Graphene Quantum Dots (Maoquan Chu):
  • Properties and Synthesis Strategies of Graphene Quantum Dots (Jiajia Zhang and Hongbin Lu)
  • Synthesis and Amino-Functionalization of the Graphene Quantum Dots (Limin Dong and Kejia Wu)
  • Plasmons in Graphene Quantum Dots (Haifeng Yin)
  • Application of Graphene Quantum Dots in Medical and Pharmaceutical Analyses (Xiaolei Zhang, Jing Wang and Gongjun Yang)
  • Graphene Quantum Dots for Food Analysis (Yongkang Ye and Xiaodong Cao)
  • Fluorescent Graphene Quantum Dots for Bioimaging (Shuhua Li, Zetan Fan, Fanglong Yuan and Louzhen Fan)
  • Graphene Quantum Dots for Drug Delivery (Yang Chen and Maoquan Chu)
  • Toxicity of Graphene Quantum Dots (Maoquan Chu)
• Volume 2: Advanced Nanomaterials for Bioimaging and Cancer Therapy (Maoquan Chu):
  • Radiolabeled Nanoparticles for In Vivo Tumor PET Imaging (Zhen Yang, Xiao Bao and Jinliang Peng)
  • Measurement and Imaging of Raman Spectroscopy with Nanoparticles (Shupeng Liu, Bing Fu, Na Chen, Zhenyi Chen, Fufei Pang, Taihao Li and Tingyun Wang)
  • Preparation of Magnetic Iron Oxide Polymerized Nanoparticles and Their Applications in Magnetic Resonance Imaging (Chunmei Song and Zhen Wang)
  • Gold Nanoparticles: A Versatile Platform for Cancer Diagnosis, Imaging and Therapy (Qiang Zhang)
  • Graphene Quantum Dots for Bioimaging and Cancer Therapy (Xiaolei Zhang and Xiaodi Yang)
  • Magnetic Nanoparticles for Cancer Therapy through Magnetic Field-Mediated Mechanical Force Stimulation (Maoquan Chu)
  • Tumor Extracellular Acidity-Sensitive Polymeric Nanocarriers for Drug Delivery and Cancer Therapy (Wei Tao, Dongdong Li, Feng Fan, Junxia Wang, Yinchu Ma and Xianzhu Yang)
  • Polysaccharides-Based Polymeric Nanoparticlesfor Drug Delivery and Tumor Therapy (Jing Yao, Fatima Zohra Dahmani, Hui Xiong, Yan Xiao, Yuanke Li and Chenfeng Xu)
  • Multifunctional Nanocomplexes for Gene Transfer and Gene Therapy (Zixiu Du)
  • Liposomal Delivery System for Small Molecular Therapeutic Drugs (Hailing Tang and Mengjie Rui)
• Volume 3: Design of Bioactive Materials for Bone Repair and Regeneration (Wei Xia and Jiang Chang):
  • Calcium Orthophosphate Coatings and Other Deposits (Sergey V Dorozhkin)
  • Biomimetic Synthesis of Nanostructured Calcium Phosphates (Wenxiao He and Martin Andersson)
  • Biological Effect of Ions in Calcium Phosphates on Bone Regeneration (Wei Xia, Jiang Chang and Håkan Engqvist)
  • Bioactive Glasses (Xiaofeng Chen and Qing Hu)
  • Biological Coatings for Implant Surface Modification (Youtao Xie, Kai Li and Xuebin Zheng)
  • Biomaterials and Biotechnologies for Treatment of Osteoporosis and Osteoporotic Injuries (Zhongru Gou, Limin Liu and Xianyan Yang)
  • Design of Silicate-Based Bioactive Materialsfor Bone Tissue Repair and Reconstruction (Haiyan Li, Lei Chen and Xin Dong)
  • Mechanical Properties of Brushite Calcium Phosphate Cements (Ingrid Ajaxon and Cecilia Persson)
  • Potential Applications of Cellulose and Its Composites in Bone Repairment and Regeneration (Ming-Guo Ma and Jie-Fang Zhu)
  • Bisphosphonate-Immobilized Biomaterials for Bone Engineering and Curing of Bone Diseases (Dmitri Ossipov and Sujit Kootala)
  • Advanced Analyses for Characterizing Bone Repair and Osseointegration (Kathryn Grandfield)

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--> Readership: This reference set is written for a wide readership including university students and researchers from diversified backgrounds such as physics, materials science, engineering, and chemistry. Both undergraduate and graduate students will find it a valuable reference book on key topics related to nanomaterials science and technology. -->
Photodynamic Cancer Therapy;Tissue Regeneration;Biomedical Imaging;Biosensors;Stem Cells Key Features:

• Covers new materials, including biodegradable and highly photothermal types, most suitable for cancer therapy and other medical applications
• Discusses recent stem cell research involving many key areas such as neuron repair
• Focuses on recently developed nano technologies, which enable extremely low levels of viral and cancer cells to be detected. These apparatuses are also portable, making the technologies much more viable clinically and individually

Published by

World Scientific Publishing Co. Pte. Ltd.

5 Toh Tuck Link, Singapore 596224

USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601

UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE

Library of Congress Cataloging-in-Publication Data

Names: Shi, Donglu, editor.

Title: The World Scientific encyclopedia of nanomedicine and bioengineering. II, Bioimplants, regenerative
medicine, and nano-cancer diagnosis and phototherapy / chief editor, Donglu Shi.

Other titles: Encyclopedia of nanomedicine and bioengineering | Bioimplants, regenerative medicine, and
nano-cancer diagnosis and phototherapy | Frontiers in nanobiomedical research ; v. 9. 2251-3965

Description: New Jersey : World Scientific, 2016. | Series: Frontiers in nanobiomedical research ; volume 9 |
Includes bibliographical references and index.

Identifiers: LCCN 2016040312 | ISBN 9789814667586 (hardcover : alk. paper)

Subjects: | MESH: Biocompatible Materials | Nanostructures | Theranostic Nanomedicine |
Tissue Engineering | Prostheses and Implants | Regeneration

Classification: LCC R856.A3 | NLM QT 37 | DDC 610.2803--dc23

LC record available at https://lccn.loc.gov/2016040312

British Library Cataloguing-in-Publication Data

A catalogue record for this book is available from the British Library.

Copyright © 2017 by World Scientific Publishing Co. Pte. Ltd.

All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the publisher.

For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher.

Typeset by Stallion Press

Email: [email protected]

Printed in Singapore

Contents

Preface

List of Contributors

Chapter 1Calcium Orthophosphate Coatings and Other Deposits
Sergey V. Dorozhkin

Chapter 2Biomimetic Synthesis of Nanostructured Calcium Phosphates
Wenxiao He and Martin Andersson

Chapter 3Biological Effect of Ions in Calcium Phosphates on Bone Regeneration
Wei Xia, Jiang Chang and Håkan Engqvist

Chapter 4Bioactive Glasses
Xiaofeng Chen and Qing Hu

Chapter 5Biological Coatings for Implant Surface Modification
Youtao Xie, Kai Li and Xuebin Zheng

Chapter 6Biomaterials and Biotechnologies for Treatment of Osteoporosis and Osteoporotic Injuries
Zhongru Gou, Limin Liu and Xianyan Yang

Chapter 7Design of Silicate-Based Bioactive Materials for Bone Tissue Repair and Reconstruction
Haiyan Li, Lei Chen and Xin Dong

Chapter 8Mechanical Properties of Brushite Calcium Phosphate Cements
Ingrid Ajaxon and Cecilia Persson

Chapter 9Potential Applications of Cellulose and Its Composites in Bone Repairment and Regeneration
Ming-Guo Ma and Jie-Fang Zhu

Chapter 10Bisphosphonate-Immobilized Biomaterials for Bone Engineering and Curing of Bone Diseases
Dmitri Ossipov and Sujit Kootala

Chapter 11Advanced Analyses for Characterizing Bone Repair and Osseointegration
Kathryn Grandfield

Index

Preface

Bioactive materials started to attract attention from the discovery of bioactive glass by Prof. Hench in 1960s. If you search “bioactive materials” in Google scholar, 510,000 references can be found. Bioactive materials are used in materials which could have chemical bonding with bone. However, it is not limited to the chemical bonding with bone tissue. In general, biomaterials which have positive biological reaction with body tissue, except bone bonding, can be regarded as bioactive materials used with purpose of dental care, medical care, pharmaceuticals, cosmetics and antibacterial application, especially in bone repair and regeneration. They can be made from different types of materials, such as ceramics, glass, glass-ceramics and composites. The global market for bioactive materials reached $792.3 million in 2012. This market is expected to grow to $1.7 billion in 2018.

There is a wide range of bioactive materials used for bone repair and regeneration, from inorganic, organic and composite materials. Among them, calcium phosphate based, calcium silicate based, bioactive glasses and their composite materials have attracted significant attention. In particular, the composition and structure of bioactive materials are important. Concerning composition, the continuous exchange ions with physiological fluid and release of ions can influence biocompatibility, further stimulate specific inflammatory and cell responses and active gene expression. The development in cellular proteomics and genomics paved the way for the next generation of bioactive materials. Structure of biomaterials generally affects the mechanical properties. Nanotechnology gives a new way to design and fabricate surface, micro- and macro-structures of materials. Newly designed structures can improve not only mechanical strength but cellular response, osteoconductivity and tissue regeneration. In certain cases, it might have advantages in osteoinductivity.

This book focuses on the frontiers in researches dedicated to bioactive materials of calcium phosphates, calcium silicates, bioactive glass, hydrogels and cellulose composites in the form of particles, coatings, scaffold, cements, etc. for bone repair and regeneration and related clinical applications.

Bioactive materials are undergoing rapid growth with the burst of nano-technology. Materials, even used in clinics, can still be improved to provide better specific applications via better design of composition and structure in both molecular level and 3D level. This book hopefully suggests potential opportunities to understand and prepare better bioactive materials.

Acknowledgments

We would like to thank the Swedish Research Council and the Natural Science Foundation of China (Grants No. 81190132) for their support.

List of Contributors

Ingrid Ajaxon
Applied Materials Science
Department of Engineering Sciences
Uppsala University
Ångströmlaboratoriet
Lägerhyddsvägen 1, 752 37 Uppsala
Sweden
[email protected]

Martin Andersson, PhD
Department of Chemistry and Chemical Engineering
Chalmers University of Technology
SE-412 96, Gothenburg, Sweden
[email protected]

Jiang Chang, PhD
Biomaterials and Tissue Engineering Research Center
Shanghai Institute of Ceramics
Chinese Academy of Sciences
1295 Dingxi Road
Shanghai 200050, China
[email protected]

Lei Chen
Shanghai Institute of Ceramics
Chinese Academy of Sciences
1295 Dingxi Road
Shanghai 200050, China
[email protected]

Xiaofeng Chen, PhD
School of Materials Science and Engineering
South China University of Technology, China
[email protected]

Xin Dong
Med-X Research Institute
School of Biomedical Engineering
Shanghai Jiao Tong University
1954 Huashan Road
Shanghai 200030, China

Sergey V. Dorozhkin, PhD
Kudrinskaja sq. 1-155, Moscow 123242, Russia
[email protected]

Håkan Engqvist, PhD
Applied Materials Science
Department of Engineering Sciences
Uppsala University
Ångströ...

Table of contents

• The World Scientific Encyclopedia of Nanomedicine and Bioengineering II
• Volume 1 Synthesis and biomedical applications of graphene quantum dots
• Volume 2 Advanced Nanomaterials for Bioimaging and Cancer Therapy
• Volume 3 Design of Bioactive Materials for Bone Repair and Regeneration