The Advanced Handbook of Methods in Evidence Based Healthcare
- 544 pages
- English
- PDF
- Available on iOS & Android
The Advanced Handbook of Methods in Evidence Based Healthcare
About This Book
?This handbook is an excellent reflection of the growing maturity and methodological sophistication of the field of Health Technology Assessment. The Handbook covers a spectrum of issues, from primary evidence (clinical trials) through reviews and meta-analysis, to identifying and filling gaps in the evidence. Up-to-date, clearly written, and well-edited, the handbook is a needed addition to any personal or professional library dealing with Health Technology Assessment.?
Professor David Banta, TNO Prevention and Health, The Netherlands
?This text presents the most advanced knowledge on methodology in health care research, and will form the backbone of many future studies? - Paula Roberts, Nurse Researcher
The `effectiveness revolution? both in research and clinical practice, has tested available methods for health services research to the extreme. How far can observational methods, routine data and qualitative methods be used in health care evaluation? What cost and outcome measures are appropriate, and how should data be gathered?
With the support of over two million pounds from the British Health Technology Assessment Research Programme, the research project for this Handbook has led to both a synthesis of all of the existing knowledge in these areas and an agenda for future debate and research.
The chapters and their authors have been selected through a careful process of peer review and provide a coherent and complete approach to the field. The handbook has been a unique collaboration between internationally regarded clinicians, statisticians, epidemiologists, social scientists, health economists and ethicists. It provides the most advanced thinking and the most authoritative resource for a state of the art review of methods of evaluating health care and will be required reading for anyone involved in health services research and management.
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Table of contents
- Cover
- Contents
- Contributors
- INTRODUCTION Methods in Evidence Based Healthcare and Health Technology Assessment: An Overview
- Part I CLINICAL TRIALS
- 1 Ethical Issues in the Design and Conduct of Randomised Controlled Trials
- 2 Ethics of Clinical Trials: Social, Cultural and Economic Factors
- 3 Factors that Limit the Number, Progress and Quality of Randomised Controlled Trials: A Systematic Review
- 4 Results of Clinical Trials and Systematic Reviews: To Whom Do They Apply?
- 5 The Placebo Effect: Methodological Process and Implications of a Structured Review
- Part II OBSERVATIONAL AND QUALITATIVE METHODS
- 6 Randomised and Non-Randomised Studies: Threats to Internal and External Validity
- 7 A Review of Observational, Quasi-Experimental and Randomised Study Designs for the Evaluation of the Effectiveness of Healthcare Interventions
- 8 The Potential Use of Routine Datasets in Health Technology Assessment
- 9 Using Routine Data to Complement and Enhance the Results of Randomised Controlled Trials
- 10 Qualitative Methods in Health Technology Assessment
- Part III MEASUREMENT OF BENEFIT AND COST
- 11 Criteria for Assessing Patient Based Outcome Measures for Use in Clinical Trials
- 12 The Use of Health Status Measures in Economic Evaluation
- 13 Collecting Resource Use Data for Costing in Clinical Trials
- 14 Eliciting Time Preferences for Health
- 15 The Conduct and Design of Questionnaire Surveys in Healthcare Research
- Part IV ANALYTICAL METHODS
- 16 Bayesian Methods
- 17 Methods for Evaluating Organisation- or Area-Based Health Interventions
- 18 Handling Uncertainty in Economic Evaluation
- 19 A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials
- 20 Simultaneous Analysis of Quality of Life and Survival Data
- Part V CONSENSUS, REVIEWS AND META-ANALYSIS
- 21 Publication and Related Biases
- 22 Meta-Analysis in Health Technology Assessment
- 23 Assessing the Quality of Reports of Randomised Trials Included in Meta-Analyses: Attitudes, Practice, Evidence and Guides
- 24 Consensus Development Methods, and their Use in Creating Clinical Guidelines
- Part VI IDENTIFYING AND FILLING GAPS IN THE EVIDENCE
- 25 Identifying New Healthcare Technologies
- 26 Timing of Assessment of Fast-Changing Health Technologies
- 27 Preliminary Economic Evaluation of Health Technologies
- Index