PART ONE
Understanding MS
1
MS Can Be Controlled
IF YOU ARE READING THIS, chances are your life is affected by MS in some way. Maybe youâve been told you have MS, or perhaps someone close to you has it. The good news is that MS can be controlled. Far from being all doom and gloom, the future can be joyous and productive.
A natural, drug-free way of self-treating is to use an all-embracing approach covering every aspect of your life and lifestyleâfood, exercise, thoughts, and emotions. In brief, it involves:
- Getting tested for food sensitivities and giving up the offending foods
- Dealing with gut problems, such as leaky gut and candida
- Switching to the Best Bet Diet
- Eating a diet high in nutrients for the brain
- Taking many nutritional supplementsâvitamins, minerals, trace elements, antioxidants, amino acids, enzymes, and essential fatty acids
- Exercising regularly
- Cleansing your body of environmental toxins
- De-stressing and rebalancing your life, and dealing with emotional and psychological hurts
- Avoiding fatigue, resting as needed, and getting sufficient sleep
- Shifting your thought patterns from negative to positive and making a decision to live life to the fullest
- Having satisfying relationships
- Maintaining your self-esteem
It may also mean receiving some complementary treatments, such as acupuncture, ayurveda, reflexology, shiatsu, or Reiki, all of which have been shown to help MS. Youâll find alphabetized information in chapter 13.
THE BEST TIME TO START IS NOW
The earlier you start this program, the better. Studies have shown that the people who benefit most from this self-help regimen are those who have been recently diagnosed. Donât wait until you get worse before you decide to try this program. Use it as an insurance policy to help prevent you from getting worse.
However, all is not lost if your illness has progressed. Some people have reversed their MS symptoms several years after diagnosis, and even in the secondary progressive stage of the disease.
It is not a cure, nor is it recognized as a treatment by the medical establishment (although there are elements in it that have had so much, and such good, scientific research that they deserve to be recognized as treatments for MS). This program can help you manage your illness. It gives you an opportunity to enjoy life fullyâeven with MS.
Most neurologists wonder why anyone would want to go on such a rigorous program as this when there are drugs to treat MS. Part of the answer is that the pharmaceuticals that have been used so farâthe âdiseasemodifyingâ drugsâcan help somewhat in reducing relapses but canât stop disease progression. Also, some people donât like having injections or the flu-like side effects of some of these drugs. Also, we donât really know the long-term effects of these drugs.
The next generation of drugs includes Tysabri, which is used to slow the progression of aggressive MS and is usually only prescribed for severe cases. Some people definitely do benefit from this drug. However, as of November 2009, there had been twenty-four cases of a brain infection called progressive multifocal leukoencephalopathy (PML) and four subsequent deaths linked to Tysabri. Because of this, Tysabri was temporarily withdrawn from the market in 2005, but was reintroduced in July 2006 with stricter safety warnings.
In the pipeline are âimmune modulatingâ drugs, such as alemtuzumab (Campath), which has had dramatically good results in trials, but also carries risks. It has been shown to stop MS in its tracks and is hailed as the most effective treatment yet for early relapsing/remitting MS, reducing attacks by 74 percent, reducing sustained disability by 71 percent, and in many cases restoring lost function. However, any benefits need to be weighed against the associated risks; doctors are hesitant to prescribe this drug except in patients in the early stages of the disease, not yet disabled, who have frequent bad attacks.
During the trials for this drug, three patients contracted a condition called idiopathic thrombocytopenic purpura, in which low blood platelet counts can lead to abnormal bleeding. This was fatal in one case. Also, nearly a quarter of the patients on alemtuzumab suffered from a thyroid autoimmune condition, with a very high prevalence of Gravesâ disease. In addition, because alemtuzumab suppresses the immune system by seriously depleting white blood cells called T-lymphocytes, vital for fighting infection, patients on this drug have an increased risk of serious bacterial, fungal, and viral infections.
All pharmaceutical drugs have side effects, and you have to weigh whether taking them is worth it; the choice is yours. Some people do bothâthey take drugs for MS and follow this bookâs management program. However, one of the benefits of the program outlined in this book is the treatments do not have unpleasant side effects. Also, unlike many of the drugs for MS, they are intended to do the exact opposite of suppressing the immune system; they are designed to actually boost, or normalize, the immune system.
As to taking certain drugs for specific MS symptoms, such as pain or bladder urgency, that, again, is up to you. Many people with MS favor a natural approach to healing, yet swear by certain drugs for specific individual symptoms.
Personally, I have never taken any disease-modifying or immune suppressant drugs to treat my MS. On the other hand, I do take ibuprofen for pain and HRT for estrogen (see chapter 15, Hormones and MS), and I would not be opposed to taking tolterodine (Detrol or Detrusitol) or Botox injections if my bladder were to worsen.
Many people with MS have successfully managed to control or even recover from MS by using techniques described in this book. When you see how effective these strategies can be, a great dark cloud lifts from your shoulders as you realize that MS doesnât have to be a life sentence, or a death sentence.
However, care is needed. This is not a cure, it is an ongoing, life-long treatment. If you go back to your old diet, lifestyle, and negative thought patterns, MS is likely to come back. The treatments, or management programs, may not all have been rigorously tested by scientific method, but there are enough studies to suggest strongly that the progression of MS can be slowed, halted, or even reversed. In addition to the scientific studies, there is also a huge amount of anecdotal evidence.
At the very least, this book suggests healthier ways to live your life.
2
What Exactly Is MS?
IF YOU KNOW what is happening in MS, itâs easier to understand why the self-help management program is relevant.
MS is described as an autoimmune, degenerative disease. The prevailing wisdom is that the body mistakenly attacks part of itself as if it were a foreign body. In MS, the myelin sheathâthe insulating layer that protects the nervesâis targeted and attacked by rogue cells in the immune system.
In a healthy immune system, white blood cells called lymphocytes are the crack troops that defend the body against attack from foreign invaders. Lymphocytes are made up of three types of cells: T cells, B cells, and NK (natural killer) cells.
Receptors on T cells are normally able to differentiate between antigensâthose invaders that cause your body to produce antibodies, such as bacteria or virusesâand your own body. Once an antigen is identified, certain T cells, called helper T cells, trigger the B cells to release those antibodies. These are molecules designed to attach to, and destroy, the chosen target antigen, or foreign body.
In MS, the T cells in the immune system have a hard time distinguishing between a foreign invader and self. The T cells mistake the bodyâs own myelin as foreign and target it in the same way they would target a bacteria or virus.
In response, the deranged T cells set off a cascade of immune events, including the release of B lymphocytes, to rid the body of the perceived threat. These B lymphocytes fire off antibodies, and this destructive process perpetuates through a cascading series of events in which the B and T cells continue to interact, creating numerous different self-antigens.
Once the lymphocytes have launched a response to an antigen, they also release masses of other white blood cells to gather at the injured or infected site. The major players in this destructive process are called leukocytes, in particular, ones called cytokines. When too many are produced, it causes inflammation and damage.
In September 2009, scientists at the prestigious Imperial College, University of London, published a paper in which they put forward the hypothesi...