Neuroendocrinology with its well defined functions, inputs, and outputs, is one of the most fertile grounds for computational modeling in neuroscience. But modeling is often seen as something of a dark art. This book aims to display the power of modeling approaches in neuroendocrinology, and to showcase its potential for understanding these complex systems.

A recurring theme in neuroendocrinology is rhythms. How are rhythms generated, and what purpose do they serve? Are these two questions inextricably intertwined?

This book is written for innocents, presuming no math beyond high school or computing beyond calculators. It seeks to lead the curious into the thinking of the modeler, providing the tools to the reader to understand models, and even develop their own, giving life to paper diagrams. The diverse chapters, from ion channels to networks, systems, and hormonal rhythms, each tell the story of a model serving to join the hard won dots of experimentation, mapping a new understanding, and revealing hidden knowledge.

Written by a team of internationally renowned researchers
Both print and enhanced e-book versions are available
Illustrated in full colour throughout

This is the fourth volume in a new Series 'Masterclass in Neuroendocrinology', a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA

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Yes, you can access Computational Neuroendocrinology by Duncan J. MacGregor, Gareth Leng, Duncan J. MacGregor, Gareth Leng in PDF and/or ePUB format, as well as other popular books in Medicine & Endocrinology & Metabolism. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Wiley

Year

2016

ISBN

9781119159452

Edition

Topic

Medicine

Subtopic

Endocrinology & Metabolism

Cover
Title Page
Copyright
Table of Contents
List of Contributors
Series Preface
Preface
About the Companion Website
Chapter 1: Bridging Between Experiments and Equations: A Tutorial on Modeling Excitability
Chapter 2: Ion Channels and Electrical Activity in Pituitary Cells: A Modeling Perspective
Chapter 3: Endoplasmic Reticulum- and Plasma-Membrane-Driven Calcium Oscillations
Chapter 4: A Mathematical Model of Gonadotropin-Releasing Hormone Neurons
Chapter 5: Modeling Spiking and Secretion in the Magnocellular Vasopressin Neuron
Chapter 6: Modeling Endocrine Cell Network Topology
Chapter 7: Modeling the Milk-Ejection Reflex
Chapter 8: Dynamics of the HPA Axis: A Systems Modeling Approach
Chapter 9: Modeling the Dynamics of Gonadotropin-Releasing Hormone (GnRH) Secretion in the Course of an Ovarian Cycle
Glossary
Index
End User License Agreement